Normal Pressure Hydrocephalus (NPH): Understanding the Causes, Symptoms, Diagnosis, and Treatment

Normal Pressure Hydrocephalus (NPH): Understanding the Causes, Symptoms, Diagnosis, and Treatment

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Focused Health Topics
Contributed byAlexander Enabnit+3 moreDec 21, 2023

Introduction: 

Normal Pressure Hydrocephalus (NPH) is a neurological disorder characterized by the abnormal accumulation of cerebrospinal fluid (CSF) in the brain's ventricles, leading to a triad of symptoms: gait disturbances, urinary incontinence, and cognitive decline. This article provides insights into the causes, symptoms, diagnosis, and treatment of NPH.

Causes: 

The exact cause of NPH is often unknown. However, several factors may contribute to its development:

  • Idiopathic: In many cases, NPH occurs spontaneously without a clear cause.
  • Secondary to Other Conditions: NPH can result from conditions like subarachnoid hemorrhage, head trauma, or meningitis.

Symptoms: 

NPH is characterized by a triad of symptoms, including:

  • Gait Disturbances: Individuals with NPH often experience difficulty walking, which may manifest as shuffling steps or a tendency to fall.
  • Urinary Incontinence: Involuntary loss of bladder control is common in NPH.
  • Cognitive Decline: Memory problems, confusion, and difficulty with executive functions may occur.

These symptoms often progress slowly and can be mistaken for other conditions, such as Alzheimer's disease or Parkinson's disease.

Diagnosis: 

Diagnosing NPH can be challenging but typically involves the following:

  • Clinical Assessment: Neurological evaluation to assess gait, cognitive function, and urinary symptoms.
  • Imaging Studies: Brain imaging, usually with a CT or MRI scan, to visualize the ventricles and rule out other conditions.
  • Lumbar Puncture (CSF Tap Test): Temporary removal of CSF through a lumbar puncture can help assess whether symptom improvement occurs, indicating NPH.

Treatment: 

Treatment for NPH often involves surgical intervention to divert or remove excess CSF:

  • Ventriculoperitoneal Shunt (VP Shunt): This surgical procedure involves placing a shunt to drain excess CSF from the brain's ventricles into the abdominal cavity, where it is absorbed.
  • Endoscopic Third Ventriculostomy (ETV): In some cases, an ETV may be performed to create a new pathway for CSF drainage within the brain.
  • Physical and Occupational Therapy: Rehabilitation therapy can help manage gait disturbances and improve overall functioning.

Conclusion: 

Normal Pressure Hydrocephalus is a complex neurological condition that can significantly impact an individual's quality of life. Early recognition, diagnosis, and appropriate treatment, often involving surgery, are crucial for managing this condition and potentially improving the patient's symptoms.

Hashtags: #NPH #Hydrocephalus #NeurologicalDisorder #MedicalCondition 


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Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Alexander Enabnit picture
Author

Alexander Enabnit

Senior Editorial Staff
Alexandra Warren picture
Author

Alexandra Warren

Senior Editorial Staff
Sandhya Kumar picture
Author

Sandhya Kumar

Editorial Staff

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