EEG Triphasic Waves: Characteristics and Clinical Significance

EEG Triphasic Waves: Characteristics and Clinical Significance

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Focused Health Topics
Contributed byAlexander Enabnit+2 moreJul 19, 2023

Introduction:

Electroencephalogram (EEG) triphasic waves are distinct waveforms observed in EEG recordings that have specific characteristics and clinical significance. Understanding these waveforms is essential for accurate interpretation and diagnosis of neurological conditions. This article provides a comprehensive exploration of EEG triphasic waves, including their features, clinical correlations, and implications in neurological evaluations.

Characteristics of EEG Triphasic Waves:

EEG triphasic waves exhibit several characteristic features:

  • Shape: Triphasic waves have a distinctive pattern with three phases, typically consisting of an initial negative deflection followed by a positive deflection and a subsequent negative deflection.
  • Morphology: The morphology of triphasic waves varies, with some displaying a symmetrical appearance and others showing asymmetry in amplitude and duration.
  • Duration: Triphasic waves are typically brief, lasting a few seconds. However, prolonged or continuous presence can indicate underlying pathology.
  • Amplitude: The amplitude of triphasic waves can range from subtle to prominent, depending on the underlying condition.
  • Distribution: Triphasic waves may be localized to specific brain regions or have a more widespread distribution across the scalp.

Clinical Correlations and Significance:

The presence of triphasic waves in EEG recordings can have clinical correlations and implications:

  • Metabolic encephalopathy: Triphasic waves are commonly associated with metabolic encephalopathy, including hepatic encephalopathy, uremic encephalopathy, and toxic-metabolic disorders. They often reflect a global dysfunction of cerebral cortical activity.
  • Neurodegenerative disorders: Triphasic waves can occur in neurodegenerative conditions such as Creutzfeldt-Jakob disease and Alzheimer's disease. They may serve as a supportive finding for these diagnoses.
  • Medication effects: Certain medications, such as lithium and some antipsychotics, can induce triphasic waves as an adverse effect. Monitoring EEG for these waveforms can help assess medication-related neurotoxicity.
  • Hypoxic-ischemic brain injury: Triphasic waves can be observed in cases of hypoxic-ischemic brain injury, indicating a compromised cerebral perfusion and neuronal dysfunction.
  • Other associations: Triphasic waves have been reported in association with metabolic abnormalities, infectious encephalitis, anoxic brain injury, and intracranial tumors.

Diagnostic Considerations:

When encountering triphasic waves in EEG recordings, it is important to consider various factors for accurate diagnosis:

  • Contextual evaluation: Clinical history, neurological examination, and other imaging or laboratory findings should be considered alongside triphasic waves to establish the underlying etiology.
  • Temporal evolution: Monitoring the appearance and evolution of triphasic waves over time can provide additional diagnostic information, as the presence, persistence, or resolution of these waveforms may be indicative of disease progression or response to treatment.

Conclusion:

EEG triphasic waves are distinct waveforms observed in EEG recordings that hold clinical significance in neurological evaluations. Understanding their characteristics, clinical correlations, and diagnostic considerations helps in accurate interpretation and aids in diagnosing and managing underlying neurological conditions.

Hashtags: #EEG #TriphasicWaves #MetabolicEncephalopathy #NeurodegenerativeDisorders


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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Alexander Enabnit picture
Author

Alexander Enabnit

Senior Editorial Staff
Alexandra Warren picture
Author

Alexandra Warren

Senior Editorial Staff

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