Calcific Band Keratopathy: Understanding the Causes, Symptoms, and Treatment of Corneal Calcium Deposits

Calcific Band Keratopathy: Understanding the Causes, Symptoms, and Treatment of Corneal Calcium Deposits

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Focused Health Topics
Contributed byAlexander Enabnit+3 moreOct 18, 2023

Introduction:

Calcific band keratopathy is a rare eye condition characterized by the deposition of calcium salts in the cornea, resulting in the formation of a white or grayish band across the corneal surface. This comprehensive article aims to explore the causes, symptoms, diagnosis, and treatment options for calcific band keratopathy to increase awareness and promote early intervention.

Understanding Calcific Band Keratopathy:

Calcific band keratopathy is also known as band keratopathy, corneal arcus, or lime deposits on the cornea. The condition typically affects the anterior cornea and may occur unilaterally or bilaterally. The deposition of calcium salts can lead to reduced vision and discomfort in affected individuals.

Causes and Risk Factors:

The exact cause of calcific band keratopathy is often multifactorial, and several risk factors may contribute to its development, including:

  • Chronic Ocular Inflammation: Conditions associated with chronic inflammation of the eye, such as uveitis or chronic keratitis, can lead to the deposition of calcium in the cornea.
  • Systemic Diseases: Certain systemic diseases, including hypercalcemia (elevated blood calcium levels), hyperparathyroidism, and renal failure, can increase the risk of calcium deposition in the cornea.
  • Previous Eye Surgery: Individuals who have undergone intraocular surgery, especially in the presence of chronic inflammation or complications, may be more susceptible to calcific band keratopathy.

Symptoms:

The symptoms of calcific band keratopathy may vary depending on the extent of calcium deposition and its impact on corneal transparency. Common symptoms include:

  • Corneal Opacity: A visible white or grayish band is observed on the corneal surface, typically located just below the corneal epithelium.
  • Reduced Vision: As the calcium deposits interfere with light transmission through the cornea, affected individuals may experience reduced visual acuity and blurring of vision.
  • Foreign Body Sensation: Some individuals may report a sensation of having a foreign body or gritty feeling in the eye.

Diagnosis:

Diagnosing calcific band keratopathy involves a comprehensive eye examination by an ophthalmologist. The following diagnostic procedures may be performed:

  • Slit-Lamp Examination: A slit-lamp biomicroscopy allows the ophthalmologist to visualize the characteristic calcium band on the corneal surface.
  • Visual Acuity Testing: To assess the clarity of vision and determine the extent of visual impairment.
  • Corneal Topography: Corneal topography may be performed to evaluate the curvature and shape of the cornea.
  • Blood Tests: Blood tests may be ordered to evaluate calcium and parathyroid hormone levels in individuals with suspected systemic involvement.

Treatment Options:

The treatment of calcific band keratopathy aims to manage symptoms and improve vision. Depending on the severity and underlying cause, treatment options may include:

  • Topical Medications: The use of topical chelating agents, such as EDTA (ethylene-diamine-tetra-acetic acid), may help dissolve the corneal calcium deposits.
  • Surgical Intervention: In cases of significant visual impairment or discomfort, surgical removal of the calcium deposits (keratectomy) may be considered.
  • Addressing Underlying Conditions: Treating any underlying systemic conditions contributing to hypercalcemia, such as hyperparathyroidism or renal dysfunction, is crucial to prevent further calcium deposition.
  • Corneal Transplantation: In severe cases with extensive corneal opacification and reduced visual acuity, corneal transplantation may be necessary to restore vision.

Prognosis:

The prognosis for calcific band keratopathy depends on the severity of corneal involvement, the underlying cause, and the response to treatment. Early detection and appropriate management can significantly improve visual outcomes and alleviate symptoms.

Conclusion:

Calcific band keratopathy is a rare eye condition characterized by the deposition of calcium salts in the cornea. Understanding its causes, symptoms, diagnosis, and treatment options can facilitate timely intervention, leading to improved vision and quality of life for affected individuals.

Hashtags: #CalcificBandKeratopathy #CornealCalciumDeposits #EyeCondition #CornealTransplantation


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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Alexander Enabnit picture
Author

Alexander Enabnit

Senior Editorial Staff
Alexandra Warren picture
Author

Alexandra Warren

Senior Editorial Staff
Nadia Debska picture
Author

Nadia Debska

Editorial Staff

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