Acromegaly: Causes, Symptoms, Diagnosis, and Treatment

Acromegaly: Causes, Symptoms, Diagnosis, and Treatment

Article
Bone, Muscle, & Joint
Focused Health Topics
Contributed byKrish Tangella MD, MBA+1 moreApr 09, 2023

Introduction:

Acromegaly is a rare hormonal disorder that results in the overproduction of growth hormone. This condition leads to abnormal growth and enlargement of the bones and tissues, especially in the hands, feet, and face. In this article, we will discuss the causes, symptoms, diagnosis, and treatment options for acromegaly.

Causes of Acromegaly:

The primary cause of acromegaly is the overproduction of growth hormone by the pituitary gland. This can be due to a benign tumor in the pituitary gland or, in rare cases, a tumor in another part of the body that produces growth hormone-releasing hormone (GHRH).

Symptoms of Acromegaly:

The symptoms of acromegaly can vary from person to person but may include:

  • Enlarged hands and feet
  • Coarse facial features, such as a protruding jaw and brow
  • Thickened skin
  • Increased body hair
  • Deepening of the voice
  • Sleep apnea
  • Headaches and vision changes
  • Joint pain and stiffness
  • Weakness and fatigue
  • Enlarged organs, such as the heart and liver

Diagnosis of Acromegaly:

The diagnosis of acromegaly usually involves a physical examination, blood tests to measure growth hormone and insulin-like growth factor-1 (IGF-1), and imaging tests, such as MRI or CT scan, to locate the tumor.

Treatment of Acromegaly:

The treatment of acromegaly aims to reduce the production of growth hormone and alleviate the symptoms. Treatment options may include:

  • Surgery to remove the tumor
  • Medications to reduce growth hormone production
  • Radiation therapy to shrink the tumor
  • Hormone replacement therapy to restore normal hormone levels

Conclusion:

Acromegaly is a rare hormonal disorder that results in abnormal growth and enlargement of bones and tissues. Symptoms may include enlarged hands and feet, coarse facial features, and joint pain. The primary cause of acromegaly is the overproduction of growth hormone by the pituitary gland. Treatment options may include surgery, medications, radiation therapy, and hormone replacement therapy. If you suspect that you may have acromegaly, it is important to seek prompt medical attention.

Hashtags: #Acromegaly #HormonalDisorder #GrowthHormone #PituitaryGland #Tumor #EnlargedHandsAndFeet #CoarseFacialFeatures #JointPain #Surgery #Medications #RadiationTherapy #HormoneReplacementTherapy

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Krish Tangella MD, MBA picture
Author

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Alexandra Warren picture
Author

Alexandra Warren

Senior Editorial Staff

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