Malignant Atrophic Papulosis (MAP)

Malignant Atrophic Papulosis (MAP)

Article
Brain & Nerve
Digestive Health
+5
Contributed byLester Fahrner, MD+1 moreJan 02, 2022

The topic Malignant Atrophic Papulosis (MAP) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Degos Disease.

Quick Summary:

  • Degos Disease (DD) is a rare disorder of the blood vessels, wherein there is abnormal blockage of small and medium-sized arteries and veins. This blockage results in cutting-off of the blood supply to various tissues and organs in the body, leading to significant damage of the tissues/organs. The condition is also known as Malignant Atrophic Papulosis (MAP)
  • The cause of the condition is unknown; however, 10% of the individuals with Degos Disease are known to have a positive family history of the same. Degos Disease can affect both children and adults
  • There are 2 forms of Degos Disease and they include:
    • Cutaneous form, when only the skin is involved. It is a milder form of DD
    • Systemic form, when the skin and other important organs of the body (such as the gastrointestinal tract, central nervous system, etc.) are involved. It is a severe form of DD
  • When the skin is affected, it results in the formation of skin lesions that can bleed, ulcerate, and slowly heal with resultant scar formation. The signs and symptoms of the systemic form of Degos Disease depend on the organs involved. When the GI tract is involved, it can result in abdominal pain, diarrhea, weight loss, and even intestinal perforation
  • Degos Disease is a complex and progressive condition that has no cure. The healthcare provider undertakes symptomatic treatment and attempts to reduce the risk of major complications, which include stroke and pericarditis
  • The prognosis of Degos Disease is based on the specific form of Degos Disease that is manifested. Individuals with milder (skin form) conditions have a relatively better prognosis in comparison to those with systemic forms

Please find comprehensive information on Degos Disease regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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