Autoimmune Hepatitis and Pregnancy: Symptoms, Risks, and Treatment

Autoimmune Hepatitis and Pregnancy: Symptoms, Risks, and Treatment

Article
Focused Health Topics
Women's Health
+2
Contributed byKrish Tangella MD, MBA+1 moreApr 17, 2023

Introduction:

Autoimmune hepatitis is a chronic liver disease caused by an autoimmune reaction where the body's immune system attacks healthy liver cells. Pregnancy can be a challenging time for women with autoimmune hepatitis, as the hormonal changes and stress on the body can exacerbate the disease. In this article, we will discuss the symptoms, risks, and treatment options for autoimmune hepatitis during pregnancy.

Symptoms:

The symptoms of autoimmune hepatitis during pregnancy are similar to those experienced outside of pregnancy and may include:

  • Fatigue
  • Abdominal discomfort or pain
  • Loss of appetite
  • Nausea and vomiting
  • Joint pain
  • Jaundice (yellowing of the skin and eyes)
  • Dark urine
  • Pale stool
  • Itching
  • Spider angiomas (tiny blood vessels on the skin)

Risks:

Pregnancy can increase the risk of complications for women with autoimmune hepatitis. These complications may include:

  • Increased risk of liver failure or cirrhosis
  • Increased risk of preterm labor and delivery
  • Increased risk of preeclampsia, a serious complication of pregnancy that can cause high blood pressure and damage to organs
  • Increased risk of fetal growth restriction or stillbirth

Treatment:

The treatment of autoimmune hepatitis during pregnancy is complex and should be managed by a team of healthcare providers, including a hepatologist and obstetrician. Treatment may include medications to control the autoimmune response and reduce inflammation in the liver. However, some medications may not be safe for use during pregnancy and may need to be adjusted or discontinued.

Diet and lifestyle changes can also help to manage the disease during pregnancy. These changes may include avoiding alcohol and certain foods that can stress the liver, getting regular exercise, and managing stress levels.

In some cases, a liver transplant may be necessary during pregnancy. This is a rare procedure that requires close monitoring and coordination between the healthcare providers.

Conclusion:

Autoimmune hepatitis can pose unique challenges for women during pregnancy, but with proper management and monitoring, many women with the disease are able to have successful pregnancies. It is important to work closely with a healthcare provider to manage the disease and prevent complications for both the mother and the baby.

Hashtags: #autoimmunehepatitis #pregnancy #symptoms #risks #treatment #medication #dietandlifestylechanges #livertransplant.

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Krish Tangella MD, MBA picture
Author

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Alexander Enabnit picture
Author

Alexander Enabnit

Senior Editorial Staff

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