Postural Orthostatic Tachycardia Syndrome

Postural Orthostatic Tachycardia Syndrome

Article
Brain & Nerve
Bone, Muscle, & Joint
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Contributed byKrish Tangella MD, MBASep 08, 2023

What are the other Names for this Condition? (Also known as/Synonyms)

  • Chronic Orthostatic Intolerance
  • Postural Tachycardia Syndrome
  • POTS (Postural Orthostatic Tachycardia Syndrome)

What is Postural Orthostatic Tachycardia Syndrome? (Definition/Background Information)

  • Postural Orthostatic Tachycardia Syndrome (POTS) is a type of dysautonomia characterized by an excessive increase in heart rate when transitioning from lying down to standing up. POTS is one of the most common forms of dysautonomia
  • This is often accompanied by various signs and symptoms, such as dizziness, lightheadedness, fatigue, and cognitive difficulties. Postural Orthostatic Tachycardia Syndrome can result in complications such as fainting and fall injuries, mental health issues, and overall decreased quality of life
  • A diagnosis of Postural Orthostatic Tachycardia Syndrome involves monitoring heart rate changes with position, assessing autonomic function, radiological imaging studies, and ruling out other conditions
  • The treatment for Postural Orthostatic Tachycardia Syndrome involves symptom management, including lifestyle modifications, increased fluid and salt intake, exercise, medications, and physical therapy
  • The prognosis for individuals with Postural Orthostatic Tachycardia Syndrome varies, with many experiencing symptom improvements over time, although long-term management may be necessary

Who gets Postural Orthostatic Tachycardia Syndrome? (Age and Sex Distribution)

  • Postural Orthostatic Tachycardia Syndrome (POTS) can affect individuals of any age
  • It is commonly observed in young to middle-aged women, particularly during adolescence and early adulthood
  • However, POTS can also occur in men and older adults
  • The condition may occur worldwide, affecting individuals of all racial and ethnic groups

What are the Risk Factors of Postural Orthostatic Tachycardia Syndrome? (Predisposing Factors)

There are several risk factors for Postural Orthostatic Tachycardia Syndrome (POTS), and these include:

  • A history of certain medical conditions such as Ehlers-Danlos syndrome, autoimmune disorders, chronic fatigue syndrome, and a previous viral infection
  • Hormonal changes
  • Genetic predisposition
  • A family history of POTS may also contribute to the development of the condition

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Postural Orthostatic Tachycardia Syndrome? (Etiology)

The exact cause of Postural Orthostatic Tachycardia Syndrome (POTS) is not fully understood.

  • It is a disorder characterized by an abnormal increase in heart rate upon assuming an upright position. Due to this, individuals with POTS may experience various symptoms, including lightheadedness, rapid heartbeat, fatigue, and fainting
  • However, several factors may play a contributory role, including autonomic nervous system dysfunction, abnormal blood volume regulation, autoimmune processes, and vascular abnormalities

What are the Signs and Symptoms of Postural Orthostatic Tachycardia Syndrome?

The common signs and symptoms of Postural Orthostatic Tachycardia Syndrome include:

  • Rapid heart rate upon standing
  • Lightheadedness or dizziness
  • Fainting or near-fainting episodes
  • Fatigue
  • Exercise intolerance
  • Brain fog
  • Gastrointestinal issues

These signs and symptoms may vary in intensity and frequency among individuals.

How is Postural Orthostatic Tachycardia Syndrome Diagnosed?

Postural Orthostatic Tachycardia Syndrome (POTS) is diagnosed on the basis of the following tests and exams:

  • Physical examination and comprehensive medical history assessment
  • Orthostatic vital signs monitoring
  • Autonomic function tests
  • Additional tests may be performed to assess cardiac function and identify any underlying conditions
  • Also, tests to exclude other potential causes of the symptoms may be undertaken

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Postural Orthostatic Tachycardia Syndrome?

Postural Orthostatic Tachycardia Syndrome can lead to various complications, including:

  • Increased risk of injuries from falls
  • Other potential complications associated with fainting episodes
  • Limited physical activity
  • Social and psychological impacts
  • Reduced quality of life

How is Postural Orthostatic Tachycardia Syndrome Treated?

The treatment of Postural Orthostatic Tachycardia Syndrome aims to manage symptoms and improve the individual's quality of life. It typically involves the following:

  • A combination of lifestyle modifications and medications to regulate heart rate and blood pressure
  • Physical conditioning exercises
  • Integrative therapies targeting autonomic dysfunction

How can Postural Orthostatic Tachycardia Syndrome be Prevented?

As the exact cause of Postural Orthostatic Tachycardia Syndrome (POTS) is not fully known, specific prevention strategies are challenging. However, maintaining a healthy lifestyle, managing underlying conditions, staying hydrated, and avoiding triggers that worsen symptoms may help reduce the risk or severity of POTS.

What is the Prognosis of Postural Orthostatic Tachycardia Syndrome? (Outcomes/Resolutions)

The prognosis of Postural Orthostatic Tachycardia Syndrome (POTS) varies among individuals.

  • While POTS can be a chronic condition, many individuals experience improvements in symptoms and quality of life with appropriate management
  • Early diagnosis, proper treatment, and ongoing support contribute to better outcomes

Additional and Relevant Useful Information for Postural Orthostatic Tachycardia Syndrome:

The following DoveMed website link is a useful resource for additional information:

http://www.dovemed.com/diseases-conditions/rare-disorders/

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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