Papulosquamous Subacute Cutaneous Lupus Erythematosus

Papulosquamous Subacute Cutaneous Lupus Erythematosus

Article
Skin Care
Diseases & Conditions
+2
Contributed byLester Fahrner, MD+1 moreAug 14, 2023

What are the other Names for this Condition? (Also known as/Synonyms)

  • Papulosquamous SCLE
  • SCLE with Papulosquamous Features
  • Subacute Cutaneous Lupus Erythematosus, Papulosquamous subtype

What is Papulosquamous Subacute Cutaneous Lupus Erythematosus? (Definition/Background Information)

  • Papulosquamous Subacute Cutaneous Lupus Erythematosus is a rare subtype of cutaneous lupus erythematosus (CLE) characterized by papules and scaly plaques on the skin. It falls under the broader subacute cutaneous lupus erythematosus (SCLE) category
  • The risk factors for the condition are not clearly understood, but the cause may be related to a dysfunctional immune system in certain individuals. Papulosquamous Subacute Cutaneous Lupus Erythematosus is mostly seen in young and middle-aged adults
  • The treatment for this form of SCLE may involve topical and systemic medications, including avoiding sun exposure. With adequate management of Papulosquamous Subacute Cutaneous Lupus Erythematosus, the outcomes are generally good

Who gets Papulosquamous Subacute Cutaneous Lupus Erythematosus? (Age and Sex Distribution)

  • Papulosquamous Subacute Cutaneous Lupus Erythematosus can affect individuals of any age, but it is more commonly observed in young to middle-aged adults
  • Both men and women can be affected
  • Worldwide, no particular race or ethnicity preference is observed

What are the Risk Factors for Papulosquamous Subacute Cutaneous Lupus Erythematosus? (Predisposing Factors)

  • The exact risk factors for Papulosquamous Subacute Cutaneous Lupus Erythematosus are not well-established
  • However, genetic factors and exposure to sunlight may play a role in its development

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Papulosquamous Subacute Cutaneous Lupus Erythematosus? (Etiology)

  • The exact cause of Papulosquamous Subacute Cutaneous Lupus Erythematosus is not fully understood
  • It is believed to result from an abnormal immune response in genetically susceptible individuals triggered by sunlight or certain medications

What are the Signs and Symptoms of Papulosquamous Subacute Cutaneous Lupus Erythematosus?

The signs and symptoms of Papulosquamous Subacute Cutaneous Lupus Erythematosus may include:

  • Small, red, or purple papules (bumps) on the skin
  • Scaly and well-defined plaques
  • Lesions may appear on sun-exposed areas like the arms, chest, and back
  • Photosensitivity, where skin worsens with sun exposure
  • Mild to moderate itching and pain

How is Papulosquamous Subacute Cutaneous Lupus Erythematosus Diagnosed?

A diagnosis of Papulosquamous Subacute Cutaneous Lupus Erythematosus may involve:

  • Physical examination, clinical evaluation of symptoms, and medical history
  • Blood tests to detect specific autoantibodies and assess organ function
  • Skin biopsy for microscopic examination of affected tissue

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Papulosquamous Subacute Cutaneous Lupus Erythematosus?

The complications of Papulosquamous Subacute Cutaneous Lupus Erythematosus may include the development of systemic lupus erythematosus (SLE) in some individuals.

How is Papulosquamous Subacute Cutaneous Lupus Erythematosus Treated?

The treatment of Papulosquamous Subacute Cutaneous Lupus Erythematosus may involve:

  • Topical corticosteroids to reduce inflammation and relieve symptoms
  • Antimalarial medications to manage skin lesions and prevent disease progression
  • Avoiding sun exposure and using sun protection measures
  • Systemic medications for more severe cases

How can Papulosquamous Subacute Cutaneous Lupus Erythematosus be Prevented?

There is no specific method to prevent Papulosquamous Subacute Cutaneous Lupus Erythematosus, but managing sun exposure and avoiding triggering medications may help reduce flares.

What is the Prognosis of Papulosquamous Subacute Cutaneous Lupus Erythematosus? (Outcomes/Resolutions)

  • The prognosis of Papulosquamous Subacute Cutaneous Lupus Erythematosus varies based on individual cases
  • Many patients can achieve remission and effectively manage their symptoms with appropriate treatment and sun protection

Additional and Relevant Useful Information for Papulosquamous Subacute Cutaneous Lupus Erythematosus:

  • Cutaneous lupus erythematosus (CLE) constitutes a wide group of autoimmune disorders primarily affecting the skin. It may or may not be associated with systemic lupus erythematosus (SLE), which may cause systemic symptoms involving the entire body and several important organs

Read more about the condition at the following link:

https://www.dovemed.com/diseases-conditions/cutaneous-lupus-erythematosus/

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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