What are the other Names for this Condition? (Also known as/Synonyms)

• MPC of the Genitourinary System
• MPC of the Urogenital System
• Myopericytoma of the Urogenital System

What is Myopericytoma of the Genitourinary System? (Definition/Background Information)

• Myopericytoma (MPC) tumor is a rare, benign tumor arising from cells that surround the blood vessels
• Myopericytoma of the Genitourinary System is rarely seen in the genitourinary tract; the genitourinary or urogenital system includes the urinary and genital organs
• The most frequent sites are the kidneys and urinary bladder

Incidence:

• Kidney tumors are seen only in adults with preference for males
• All races and ethnic groups are at risk

Risk factors:

• When myopericytoma forms at other locations (outside the urogenital system), a positive family history has been noted
• However, so far, no family history is recorded for Myopericytoma of the Genitourinary System

Cause:

• The cause of tumor formation is unknown
• Generally, genetic abnormalities at other sites are reported, of which frequently observed is PDGFRB gene mutation. But these are not reported in tumors involving the genitourinary system

Signs and symptoms:

• The tumors can arise in the kidney and urinary bladder
• Depending on the location of the tumor the signs and symptoms vary
• Kidney tumors may remain asymptomatic
• Individuals with tumors in the urinary bladder present blood in urine, painful urination, and changes in urination frequency
• Kidney tumors are typically well-defined
• Genitourinary tract tumors may range in size from 18-73 mm

Diagnosis: In kidney, these are discovered incidentally, when the patient is examined for other medical conditions.

• Blood and urine tests
• Radiological studies
  • Ultrasound of abdomen
  • CT and MRI scan of abdomen
• Tissue biopsy of the tumor mass can help achieve a definitive diagnosis:

Complications:

• Emotional stress
• Incomplete removal can rarely result in tumor recurrence

Treatment:

• Treatment depends on the location and the size of the tumor
• Wait and watch approach for small and asymptomatic tumors
• Surgery to remove the tumor for large and symptomatic tumors

Prevention: Presently, it is not possible to prevent the formation of Myopericytoma of the Genitourinary System.

Prognosis:

• Benign tumor; complete tumor removal via surgery is curative
• Recurrence is very uncommon

Outside the genitourinary system, malignant tumors have been very infrequently noted with poor prognosis.