Mucosal Discoid Lupus Erythematosus

Mucosal Discoid Lupus Erythematosus

Article
Sexual Health
Skin Care
+2
Contributed byLester Fahrner, MD+1 moreAug 14, 2023

What are the other Names for this Condition? (Also known as/Synonyms)

  • Mucocutaneous Discoid Lupus Erythematosus
  • Mucocutaneous DLE
  • Mucosal DLE

What is Mucosal Discoid Lupus Erythematosus? (Definition/Background Information)

  • Mucosal Discoid Lupus Erythematosus (Mucosal DLE) is a type of cutaneous lupus erythematosus (CLE) of subtype termed chronic cutaneous lupus erythematosus (CCLE), primarily affecting the mucous membranes
  • This causes inflammatory lesions and ulcers in areas such as the mouth, nose, and genitals. The signs and symptoms of Mucosal Discoid Lupus Erythematosus include pain, redness, and ulceration of mucous membranes
  • Diagnosing Mucosal Discoid Lupus Erythematosus involves clinical evaluation, laboratory tests, and skin biopsies. Treatment may include topical or systemic medications to manage inflammation and symptoms
  • The prognosis of this mucocutaneous condition varies; while Mucosal Discoid Lupus Erythematosus is generally not life-threatening, long-term management is often required to control symptoms and prevent complications

Who gets Mucosal Discoid Lupus Erythematosus? (Age and Sex Distribution)

  • Mucosal Discoid Lupus Erythematosus can occur in individuals of all ages but is more commonly seen in adults
  • Both males and females can be affected
  • Worldwide, no particular race or ethnicity preference is observed

What are the Risk Factors for Mucosal Discoid Lupus Erythematosus? (Predisposing Factors)

  • The exact risk factors for Mucosal Discoid Lupus Erythematosus are not well-defined, but genetics and immune system abnormalities may play a contributory role

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Mucosal Discoid Lupus Erythematosus? (Etiology)

  • Like other forms of cutaneous lupus, the exact cause of Mucosal Discoid Lupus Erythematosus is believed to involve an autoimmune reaction targeting mucosal tissues
  • Mucosal DLE is in the subtype of cutaneous lupus erythematosus (CLE ) termed chronic cutaneous lupus erythematosus (CCLE)

What are the Signs and Symptoms of Mucosal Discoid Lupus Erythematosus?

The signs and symptoms of Mucosal Discoid Lupus Erythematosus may include:

  • Red raised and scaly lesions on mucous membranes (mouth, nose, throat, or genitalia)
  • Pain, discomfort, and ulceration in affected areas

How is Mucosal Discoid Lupus Erythematosus Diagnosed?

A diagnosis of Mucosal Discoid Lupus Erythematosus involves:

  • Physical exam and medical history evaluation
  • Examination of mucosal surfaces for characteristic lesions
  • Blood tests to assess autoantibodies and overall health
  • Biopsy of the affected tissue for microscopic evaluation

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Mucosal Discoid Lupus Erythematosus?

The complications of Mucosal Discoid Lupus Erythematosus may include scarring, difficulty in eating, and potential impact on overall quality of life.

How is Mucosal Discoid Lupus Erythematosus Treated?

The treatment of Mucosal Discoid Lupus Erythematosus may involve:

  • Topical corticosteroids to reduce inflammation and promote healing
  • Immunosuppressive medications for more severe cases
  • Lifestyle modifications and sun protection to manage symptoms

How can Mucosal Discoid Lupus Erythematosus be Prevented?

There is no specific method to prevent Mucosal Discoid Lupus Erythematosus, but avoiding triggers and sun protection may help manage the symptoms.

What is the Prognosis of Mucosal Discoid Lupus Erythematosus? (Outcomes/Resolutions)

  • The prognosis for Mucosal Discoid Lupus Erythematosus is generally good with appropriate management
  • Most individuals are able to achieve control over their symptoms and prevent exacerbations

Additional and Relevant Useful Information for Mucosal Discoid Lupus Erythematosus:

  • Cutaneous lupus erythematosus (CLE) constitutes a wide group of autoimmune disorders primarily affecting the skin. It may or may not be associated with systemic lupus erythematosus (SLE), which may cause systemic symptoms involving the entire body and several important organs

Read more about the condition at the following link:

https://www.dovemed.com/diseases-conditions/cutaneous-lupus-erythematosus/

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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