What are the other Names for this Condition? (Also known as/Synonyms)

• Cervical Mesonephric Remnants Hyperplasia
• Hyperplasia of Mesonephric Remnants of Uterine Cervix
• Mesonephric Remnants and Hyperplasia of Uterine Cervix

What is Mesonephric Remnants Hyperplasia of Uterine Cervix? (Definition/Background Information)

• Mesonephric Remnants Hyperplasia of Uterine Cervix refers to a benign and abnormal growth of mesonephric duct remnants within the cervix. The mesonephric duct remnants form during embryological growth and development
• The condition may be observed in both children and adult women. However, in almost all cases, Cervical Mesonephric Remnants Hyperplasia is incidentally diagnosed during a cone biopsy or following a hysterectomy
• There are no clearly established risk factors for Mesonephric Remnants Hyperplasia of Uterine Cervix. The mesonephric ducts form during fetal development during pregnancy; the persistence of these ducts in the child following its birth can result in the condition
• No significant signs and symptoms or complications are generally noted; however, occasionally the Mesonephric Remnants Hyperplasia of Cervix is associated with cancer
• Treatment course may include a ‘wait and watch’ approach or surgical intervention. In general, the prognosis of Mesonephric Remnants Hyperplasia of Uterine Cervix is excellent with adequate treatment

Who gets Mesonephric Remnants Hyperplasia of Uterine Cervix? (Age and Sex Distribution)

• The incidence of the presence of mesonephric duct remnants among adults is estimated to be between 10-20%
• Studies also indicate that around 40% of newborn and young children may show the presence of mesonephric duct remnants in the uterine cervix. Such mesonephric duct remnants often disappear as the child moves into adulthood
• However, mesonephric hyperplasia is observed in adult women; commonly in women between 20-35 years (reproductive age group) and over 48-50 years (after menopause)
• There is no known ethnic or racial preference

What are the Risk Factors for Mesonephric Remnants Hyperplasia of Uterine Cervix? (Predisposing Factors)

• No definitive risk factors have been identified for Mesonephric Remnants Hyperplasia of Uterine Cervix

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases ones chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Mesonephric Remnants Hyperplasia of Uterine Cervix? (Etiology)

Currently, the exact cause of Mesonephric Remnants Hyperplasia of Uterine Cervix is unknown.

• During fetal growth and development, the formation of mesonephric ducts (Gartner ducts) take place. These are generally known to disappear after childbirth
• However, in case they are present (in the child) following delivery of the child, they are termed mesonephric duct remnants
• An abnormal growth or proliferation of the mesonephric duct remnants is termed mesonephric hyperplasia

What are the Signs and Symptoms of Mesonephric Remnants Hyperplasia of Uterine Cervix?

• Generally, no signs and symptoms of Mesonephric Remnants Hyperplasia of Uterine Cervix are observed and a majority of the women are asymptomatic
• In some cases, the presence of a mass may be observed
• Abnormal vaginal bleeding

How is Mesonephric Remnants Hyperplasia of Uterine Cervix Diagnosed?

A diagnosis of Mesonephric Remnants Hyperplasia of Uterine Cervix may involve the following steps:

• Evaluation of the individual’s medical history and a thorough physical (pelvic) examination
• Ultrasound scan of the abdomen
• CT or CAT scan with contrast of the abdomen and pelvis. This radiological procedure creates detailed 3-dimensional images of structures inside the body
• MRI scans of the abdomen and pelvis: Magnetic resonance imaging (MRI) uses a magnetic field to create high-quality pictures of certain parts of the body, such as tissues, muscles, nerves, and bones. These high-quality pictures may reveal the presence of the mass
• Colposcopy: The cervix is examined with an instrument, called a colposcope. This helps the physician get a magnified view of the cervix

Cervical biopsy: It is the process of removing tissue for examination. In the case of mesonephric remnants hyperplasia, a complete excision and removal of the mass can help in the process of a biopsy, as well as be a means for treating the condition.

A pathologist looks at the tissue sample under a microscope, to detect any evidence of cancer. Types of cervical biopsies include:

• Colposcopic biopsy: The abnormal areas of the cervix are visualized with a colposcope. After numbing the cervix with a local anesthetic, an instrument, called a biopsy forceps, is used to get a tissue sample.  Mild cramps, pain, and some light bleeding, may occur following the procedure
• Endocervical curettage (endocervical scraping): The curette is an instrument that can be used to scrape out tissue. Using a curette, cells are scraped out from the endocervix (the inner part of the cervix, close to the uterus/womb) and examined under a microscope. Mild pain and bleeding may be present following the procedure

Note:

• Mesonephric Remnants Hyperplasia of Cervix is almost always an incidental finding, either during a cone biopsy or following a hysterectomy.
• The condition can pose diagnostic challenges due to its rarity

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Mesonephric Remnants Hyperplasia of Uterine Cervix?

• Significant complications from Mesonephric Remnants Hyperplasia of Cervix are generally not noted, because it is a benign condition in most cases
• A few isolated cases have been associated with adenocarcinoma

How is Mesonephric Remnants Hyperplasia of Uterine Cervix Treated?

Treatment measures for Mesonephric Remnants Hyperplasia of Uterine Cervix may include the following:

• If there are no symptoms, then the healthcare provider may chose not to treat the condition in some cases
• Surgical intervention with complete excision can result in a complete cure
• Post-operative care is important: Minimum activity level is to be ensured until the surgical wound heals
• Follow-up care with regular screening and check-ups are important

How can Mesonephric Remnants Hyperplasia of Uterine Cervix be Prevented?

• Current medical research has not established a method of preventing Mesonephric Remnants Hyperplasia of Uterine Cervix
• Medical screening at regular intervals with scans and physical examinations are advised

What is the Prognosis of Mesonephric Remnants Hyperplasia of Uterine Cervix? (Outcomes/Resolutions)

• The prognosis of Mesonephric Remnants Hyperplasia of Uterine Cervix is excellent with adequate treatment (including surgery if required), since in a majority of cases it is a benign condition
• Very rarely, it can give rise to a mesonephric adenocarcinoma. Nevertheless, it is important to note that Cervical Mesonephric Remnants Hyperplasia is a benign condition

Additional and Relevant Useful Information for Mesonephric Remnants Hyperplasia of Uterine Cervix:

Please visit our Women’s Health center for more physician-approved health information:

http://www.dovemed.com/healthy-living/womens-health/