Localized Acute Cutaneous Lupus Erythematosus

Localized Acute Cutaneous Lupus Erythematosus

Article
Skin Care
Diseases & Conditions
+1
Contributed byLester Fahrner, MD+1 moreAug 14, 2023

What are the other Names for this Condition? (Also known as/Synonyms)

  • Acute Cutaneous Lupus Erythematosus, Localized subtype
  • Localized ACLE

What is Localized Acute Cutaneous Lupus Erythematosus? (Definition/Background Information)

  • Localized Acute Cutaneous Lupus Erythematosus is a form of acute cutaneous lupus erythematosus (ACLE) that affects only minimal areas of the skin. It presents as skin lesions and is typically limited to specific body areas
  • The risk factors for the condition are not clearly understood, but the cause may be related to a dysfunctional immune system in certain individuals. Localized Acute Cutaneous Lupus Erythematosus is mostly seen in young and middle-aged adults
  • The treatment for this form of ACLE may involve topical and systemic medications, including avoiding sun exposure. With adequate management of Localized Acute Cutaneous Lupus Erythematosus, the outcomes are generally good

Who gets Localized Acute Cutaneous Lupus Erythematosus? (Age and Sex Distribution)

  • Localized Acute Cutaneous Lupus Erythematosus can occur at any age, but it most commonly affects adults between the ages of 20 and 40
  • Women are more prone to this condition than men
  • Worldwide, no particular race or ethnicity preference is observed

What are the Risk Factors for Localized Acute Cutaneous Lupus Erythematosus? (Predisposing Factors)

  • The exact risk factors for Localized Acute Cutaneous Lupus Erythematosus are not fully understood, but genetic predisposition and exposure to UV radiation may play a role in its development

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Localized Acute Cutaneous Lupus Erythematosus? (Etiology)

The underlying cause of Localized Acute Cutaneous Lupus Erythematosus is an abnormal immune response, leading to inflammation in the skin.

What are the Signs and Symptoms of Localized Acute Cutaneous Lupus Erythematosus?

The signs and symptoms of Localized Acute Cutaneous Lupus Erythematosus include:

  • Red, scaly, and raised skin lesions
  • Lesions with indistinct borders
  • Itchy or painful skin
  • Skin sensitivity to sunlight

How is Localized Acute Cutaneous Lupus Erythematosus Diagnosed?

A diagnosis of Localized Acute Cutaneous Lupus Erythematosus involves a combination of the following:

  • Physical examination and evaluation of skin lesions
  • Medical history and assessment of symptoms
  • Blood tests to detect specific antibodies and assess overall immune function
  • Skin biopsy for microscopic examination of affected tissue

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Localized Acute Cutaneous Lupus Erythematosus?

Localized Acute Cutaneous Lupus Erythematosus rarely progresses to systemic lupus erythematosus (SLE), a more severe form of the disease affecting multiple organs.

How is Localized Acute Cutaneous Lupus Erythematosus Treated?

The treatment of Localized Acute Cutaneous Lupus Erythematosus may involve:

  • Topical corticosteroids to reduce inflammation and itching
  • Sun protection and avoidance of UV radiation
  • Immune-suppressing medications for severe cases

How can Localized Acute Cutaneous Lupus Erythematosus be Prevented?

The prevention measures for Localized Acute Cutaneous Lupus Erythematosus may include:

  • Minimizing sun exposure and using sunscreen
  • Managing stress and maintaining a healthy lifestyle
  • Regular follow-up with a healthcare provider for early detection and management

What is the Prognosis of Localized Acute Cutaneous Lupus Erythematosus? (Outcomes/Resolutions)

With appropriate treatment and sun protection, most individuals with Localized Acute Cutaneous Lupus Erythematosus can achieve remission and experience a good prognosis.

Additional and Relevant Useful Information for Localized Acute Cutaneous Lupus Erythematosus:

  • Cutaneous lupus erythematosus (CLE) constitutes a wide group of autoimmune disorders primarily affecting the skin. It may or may not be associated with systemic lupus erythematosus (SLE), which may cause systemic symptoms involving the entire body and several important organs

Read more about the condition at the following link:

https://www.dovemed.com/diseases-conditions/cutaneous-lupus-erythematosus/

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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