What are the other Names for this Condition? (Also known as/Synonyms)

• Lipid-Rich Variant of Urothelial Carcinoma
• Lipid Urothelial Carcinoma

What is Lipid-Rich Urothelial Carcinoma? (Definition/Background Information)

• Lipid-Rich Urothelial Carcinoma is an extremely rare and aggressive subtype of invasive urothelial carcinoma (UCC), a form of malignancy of the urothelium (urothelial cells that line the urothelial tract)
• Lipid-Rich Urothelial Carcinoma is diagnosed under the microscope, on examination of the cancer cells by a pathologist. The classification of the tumor is important, as it may dictate the type of treatments to be provided and the overall outcomes
• The exact cause of Lipid-Rich Urothelial Carcinoma is presently unknown. The condition is noted in middle-aged and older adults between 56 and 80 years, with a male predominance. Many contributory factors, such as smoking (a significant risk factor), occupational exposure to chemicals, and prior radiation therapy, are noted
• The signs and symptoms of Lipid-Rich Urothelial Carcinoma usually include blood in urine (hematuria), burning sensation on urination, and back pain. Complications of the tumor include metastasis to the lymph nodes and other organs. The malignancy frequently coexists with other UCC subtypes
• The treatment may include surgery, chemotherapy, and radiation therapy based on the healthcare provider’s assessment. Individuals with Lipid-Rich Urothelial Carcinoma typically have poor prognoses; the tumors are also known to recur following surgery. The 5-year survival rate is around 42%