Hidradenoma Papilliferum of Eyelid

Hidradenoma Papilliferum of Eyelid

Article
Skin Care
Women's Health
+2
Contributed byLester Fahrner, MD+1 moreJun 08, 2021

What are the other Names for this Condition? (Also known as/Synonyms)

  • Papillary Hidradenoma of Eyelid

What is Hidradenoma Papilliferum of Eyelid? (Definition/Background Information)

  • Hidradenoma Papilliferum is a rare benign tumor of the sweat glands. It usually arises from the apocrine sweat gland
  • There are three different types of sweat glands in the skin. These include the following:
    • Apocrine sweat glands
    • Eccrine sweat glands
    • Sebaceous sweat glands
  • Hidradenoma Papilliferum of Eyelid is a slow-growing and usually solitary tumor that occurs as a painless papule or mass. It is a very rare condition that is seen in the eyelid (upper eyelid) of middle-aged women
  • The cause of Hidradenoma Papilliferum of Eyelid is largely unknown, though Caucasians have a higher risk for the condition
  • In a majority of cases, no treatment in necessary, unless it causes worrisome symptoms or presents cosmetic concerns in the individual
  • A simple surgical excision of the tumor is considered curative. The prognosis for Hidradenoma Papilliferum is excellent with suitable treatment

Who gets Hidradenoma Papilliferum of Eyelid? (Age and Sex Distribution)

  • Hidradenoma Papilliferum of Eyelid is a very uncommon condition that is generally present in young or middle-age women in the age range of 20-50 years
  • Males are also rarely affected; the frequency of incidence is much less
  • Individuals of all racial and ethnic background may be affected, though the tumor is only infrequently seen in African Americans. It is more common in Caucasians

What are the Risk Factors for Hidradenoma Papilliferum of Eyelid? (Predisposing Factors)

Currently, the following risk factor has been identified for Hidradenoma Papilliferum of Eyelid:

  • Middle-aged women
  • Caucasians

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases ones chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Hidradenoma Papilliferum of Eyelid? (Etiology)

  • The cause of development of Hidradenoma Papilliferum of Eyelid is unknown
  • Research is currently being undertaken to identify the relevant causal factors

What are the Signs and Symptoms of Hidradenoma Papilliferum of Eyelid?

The signs and symptoms of Hidradenoma Papilliferum of Eyelid include:

  • It usually occurs as a single papule (lump) on the upper eyelid
  • It is a slow-growing tumor and is usually painless and non-itchy
  • Some tumors can be pigmented
  • The tumor can also cause:
    • Warmth and redness of the eye
    • Excessive tear formation
    • Presence of foreign body sensation within the eye
    • Discomfort and pain

How is Hidradenoma Papilliferum of Eyelid Diagnosed?

A diagnosis of Hidradenoma Papilliferum of Eyelid may involve the following:

  • A thorough medical history and physical examination
  • Culture studies to exclude infection of the eye
  • Dermoscopy: It is a diagnostic tool where a dermatologist examines the skin using a special magnified lens
  • Wood’s lamp examination: In this procedure, the healthcare provider examines the skin using ultraviolet light. It is performed to examine the change in skin pigmentation
  • Skin biopsy: A skin tissue biopsy is performed and sent to a laboratory for a pathological examination. The pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Hidradenoma Papilliferum of Eyelid?

Hidradenoma Papilliferum of Eyelid is a benign lesion that may cause the following complications:

  • The tumors can ulcerate and bleed. This can cause secondary bacterial or fungal infections to develop (superimposed infections)
  • Some individuals may have concerns regarding their cosmetic appearance
  • In rare cases, some tumors may transform into malignant forms

How is Hidradenoma Papilliferum of Eyelid Treated?

The treatment of Hidradenoma Papilliferum of Eyelid may involve the following:

  • In a majority of cases, the healthcare provider may recommend a simple surgical excision to remove the tumor; this can result in a cure
  • Follow-up care with regular screening and check-ups are important and encouraged

How can Hidradenoma Papilliferum of Eyelid be Prevented?

Currently, there are no known methods to prevent Hidradenoma Papilliferum occurrence.

What is the Prognosis of Hidradenoma Papilliferum of Eyelid? (Outcomes/Resolutions)

The prognosis for Hidradenoma Papilliferum is excellent with appropriate treatment, since it is a benign tumor.

Additional and Relevant Useful Information for Hidradenoma Papilliferum of Eyelid:

  • There is no evidence to prove that oily foods and chocolate-based products have an influence on Hidradenoma Papilliferum of Eyelid formation
  • Cleaning the skin too hard with strong chemicals or soaps may aggravate the skin condition. Care must be taken avoid strong soaps and chemicals that could potentially worsen the condition
  • The presence of dirt on the body is not a causative factor for the condition. However, it helps to be clean and hygienic, which may help the condition from getting worse
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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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