What are the other Names for this Condition? (Also known as/Synonyms)

• FHI (Fuchs Heterochromic Iridocyclitis)
• Fuchs Heterochromic Cyclitis
• Fuchs Heterochromic Uveitis

What is Fuchs Heterochromic Iridocyclitis? (Definition/Background Information)

• Fuchs Heterochromic Iridocyclitis (FHI) is an unusual form of chronic (long-lasting) uveitis. Uveitis is swelling and irritation of the middle layer of the eye
• Diagnosis of FHI is considered in people with floaters, vision loss, and heterochromia
• FHI often affects young adults and most often involves a single eye
• People with FHI are at risk for cataract, glaucoma, and vitreous opacity (clouding of the jelly-like substance in the eyeball)

(Source: Fuchs Heterochromic Iridocyclitis; Genetic and Rare Diseases Information Center (GARD) of National Center for Advancing Translational Sciences (NCATS), USA.)

Who gets Fuchs Heterochromic Iridocyclitis? (Age and Sex Distribution)

• Fuchs Heterochromic Iridocyclitis is a rare disorder. The presentation of symptoms are seen during young adulthood
• Both males and females may be affected
• Worldwide, individuals of all racial and ethnic groups may be affected

What are the Risk Factors for Fuchs Heterochromic Iridocyclitis? (Predisposing Factors)

• Currently, no risk factors have been clearly identified for Fuchs Heterochromic Iridocyclitis

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Fuchs Heterochromic Iridocyclitis? (Etiology)

The exact cause of development of Fuchs Heterochromic Iridocyclitis is presently unknown.

What are the Signs and Symptoms of Fuchs Heterochromic Iridocyclitis?

The signs and symptoms of Fuchs Heterochromic Iridocyclitis (FHI) include:

• Chronic uveitis (the swelling and irritation of the middle layer of the eye), often involving a single eye
• Presence of floaters
• Vision loss
• Heterochromia

People with FHI are at risk for cataract, glaucoma, and vitreous opacity (clouding of the jelly-like substance in the eyeball).

(Source: Fuchs Heterochromic Iridocyclitis; Genetic and Rare Diseases Information Center (GARD) of National Center for Advancing Translational Sciences (NCATS), USA.)

How is Fuchs Heterochromic Iridocyclitis Diagnosed?

Fuchs Heterochromic Iridocyclitis is diagnosed on the basis of the following information:

• Complete physical examination
• Thorough medical history evaluation
• Assessment of signs and symptoms
• Laboratory tests
• Imaging studies
• Biopsy studies, if necessary

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Fuchs Heterochromic Iridocyclitis?

The complications of Fuchs Heterochromic Iridocyclitis may include:

• Cataract
• Glaucoma
• Loss of vision

Complications may occur with or without treatment, and in some cases, due to treatment also.

How is Fuchs Heterochromic Iridocyclitis Treated?

The treatment for Fuchs Heterochromic Iridocyclitis is usually given to manage the signs and symptoms and any complications that develops.

How can Fuchs Heterochromic Iridocyclitis be Prevented?

• Currently, Fuchs Heterochromic Iridocyclitis may not be preventable, since the cause of the disorder is unknown
• Regular medical screening at periodic intervals with tests and physical examinations are recommended

What is the Prognosis of Fuchs Heterochromic Iridocyclitis? (Outcomes/Resolutions)

• The prognosis of Fuchs Heterochromic Iridocyclitis is dependent upon the severity of the signs and symptoms and associated complications, if any
• Individuals with mild conditions have better prognosis than those with severe symptoms and complications
• Typically, the prognosis may be assessed on a case-by-case basis

Additional and Relevant Useful Information for Fuchs Heterochromic Iridocyclitis:

The following DoveMed website link is a useful resource for additional information:

http://www.dovemed.com/diseases-conditions/rare-disorders/