Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus

Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus

Article
Skin Care
Women's Health
+2
Contributed byLester Fahrner, MD+1 moreSep 26, 2023

What are the other Names for this Condition? (Also known as/Synonyms)

  • EM-like SCLE
  • Erythema Multiforme-like SCLE
  • Rowell Syndrome

What is Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus? (Definition/Background Information)

  • Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus, also known as Rowell Syndrome, is a subtype of subacute cutaneous lupus erythematosus (SCLE) that exhibits skin lesions resembling those seen in erythema multiforme (an acute, benign skin condition with sudden onset)
  • The risk factors for the condition are not well known, but the cause may be related to a dysfunctional immune system. Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus is mostly seen in women
  • The treatment for this form of SCLE may involve topical and systemic medications, including avoiding sun exposure. With adequate management of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus, the outcomes are generally good

Who gets Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus? (Age and Sex Distribution)

  • Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus can affect individuals of all ages, but it is more commonly seen in adults, with a higher prevalence in females
  • Worldwide, no particular race or ethnicity preference is observed

What are the Risk Factors for Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus? (Predisposing Factors)

  • The exact risk factors for Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus are not fully understood
  • However, individuals with a history of lupus or other autoimmune diseases may be at higher risk

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus? (Etiology)

The precise cause of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus is not fully understood, but it is thought to involve an abnormal immune response triggered by environmental factors or medications.

What are the Signs and Symptoms of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus?

The signs and symptoms of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus may include:

  • Target-like skin lesions with a central red area and surrounding pale ring
  • Skin rash with raised edges and possible scaling
  • Itching and discomfort
  • Sun sensitivity

How is Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus Diagnosed?

A diagnosis of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus may involve:

  • Physical examination, clinical evaluation of symptoms, and medical history
  • Blood tests to detect specific autoantibodies and assess organ function
  • Skin biopsy for microscopic examination of affected tissue

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus?

The complications of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus may include infection, scarring, and emotional distress due to visible skin changes.

How is Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus Treated?

The treatment of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus may involve:

  • Topical or systemic corticosteroids to reduce inflammation
  • Antimalarial drugs for more severe cases
  • Sun protection and avoiding triggers
  • Supportive measures to manage symptoms and improve skin health

How can Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus be Prevented?

There is no specific method to prevent Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus. However, managing underlying lupus and avoiding known triggers may help reduce the risk of flares.

What is the Prognosis of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus? (Outcomes/Resolutions)

  • The prognosis of Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus varies depending on individual cases
  • Many patients can achieve remission and effectively manage their condition with appropriate and timely treatment

Additional and Relevant Useful Information for Erythema Multiforme-like Subacute Cutaneous Lupus Erythematosus:

  • Cutaneous lupus erythematosus (CLE) constitutes a wide group of autoimmune disorders primarily affecting the skin. It may or may not be associated with systemic lupus erythematosus (SLE), which may cause systemic symptoms involving the entire body and several important organs

Read more about the condition at the following link:

https://www.dovemed.com/diseases-conditions/cutaneous-lupus-erythematosus/

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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