What are the other Names for this Condition? (Also known as/Synonyms)

• DFSP of Breast
• Mammary Dermatofibrosarcoma Protuberans
• Mammary DFSP

What is Dermatofibrosarcoma Protuberans of Breast? (Definition/Background Information)

• Dermatofibrosarcoma protuberans (DFSP) is a rare cancer affecting the skin, typically on the trunk or limbs. When it occurs in the breast, it is known as Dermatofibrosarcoma Protuberans of Breast
• Dermatofibrosarcoma protuberans is a slow-growing tumor that rarely spreads to other body parts but can be locally aggressive. The signs and symptoms of DFSP of the Breast may include the presence of a lump in the breast that presents no pain and redness of breast skin
• A treatment for Dermatofibrosarcoma Protuberans of Breast may involve surgery to remove the tumor mass. This may be followed by radiation therapy. In most cases, the prognosis is improved with early detection and adequate treatment

Who gets Dermatofibrosarcoma Protuberans of Breast? (Age and Sex Distribution)

• Dermatofibrosarcoma Protuberans of Breast can occur in any individual, but it is more common in adults between the ages of 20 and 50 years old
• Both males and females may be affected
• Presently, no racial or ethnic group preference is reported

What are the Risk Factors for Dermatofibrosarcoma Protuberans of Breast? (Predisposing Factors)

• The risk factors for Dermatofibrosarcoma Protuberans of Breast are typically unknown, but individuals with a history of DFSP or other skin cancers may be at a higher risk

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Dermatofibrosarcoma Protuberans of Breast? (Etiology)

The exact cause of formation of Dermatofibrosarcoma Protuberans of Breast is unknown, but it is believed to be caused by genetic mutations in the cells of the skin.

What are the Signs and Symptoms of Dermatofibrosarcoma Protuberans of Breast?

The signs and symptoms of Dermatofibrosarcoma Protuberans of Breast may include:

• A painless lump or mass in the breast
• Thickening or puckering of the skin
• Redness or discoloration of the skin
• Ulceration or bleeding from the tumor

How is Dermatofibrosarcoma Protuberans of Breast Diagnosed?

A diagnosis of Dermatofibrosarcoma Protuberans (DFSP) of Breast may involve the following:

• Clinical examination and medical history evaluation
• Assessment of the presenting signs and symptoms
• Laboratory tests

DFSP of the Breast is typically diagnosed through a biopsy of the tumor, which is then examined under a microscope by a pathologist.

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Dermatofibrosarcoma Protuberans of Breast?

The complications of Dermatofibrosarcoma Protuberans of Breast may include:

• Local recurrence of the tumor
• Spread of cancer to nearby tissues or lymph nodes
• Development of other skin cancers

How is Dermatofibrosarcoma Protuberans of Breast Treated?

• Dermatofibrosarcoma Protuberans of Breast is typically treated with surgery to remove the tumor, followed by radiation therapy to prevent a recurrence
• In some cases, chemotherapy or targeted therapy may also be used

How can Dermatofibrosarcoma Protuberans of Breast be Prevented?

Presently, Dermatofibrosarcoma Protuberans of Breast cannot be prevented, although prompt detection and treatment can improve the prognosis and reduce the risk of complications.

What is the Prognosis of Dermatofibrosarcoma Protuberans of Breast? (Outcomes/Resolutions)

• The prognosis for Dermatofibrosarcoma Protuberans of Breast is generally good if the tumor is detected early and treated aggressively
• However, if the tumor has spread to other parts of the body or recurs after treatment, the prognosis may be adversely affected

Additional and Relevant Useful Information for Dermatofibrosarcoma Protuberans of Breast:

The following link is a useful resource for information on dermatofibrosarcoma protuberans (DFSP) on DoveMed:

https://www.dovemed.com/diseases-conditions/dermatofibrosarcoma-protuberans-dfsp/