What are the other Names for this Condition? (Also known as/Synonyms)

• Maumenee Syndrome

What is Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome? (Definition/Background Information)

• Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome is an extremely rare congenital disorder of unknown prevalence
• The condition is characterized by cleft lower lip, cleft corners of the eyes (lateral canthi), and retinal abnormalities

Who gets Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome? (Age and Sex Distribution)

• Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome is a very rare congenital disorder. The presentation of symptoms may occur at birth
• The prevalence and gender/racial bias for the occurrence of the disorder is not known

What are the Risk Factors for Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome? (Predisposing Factors)

• Currently, no risk factors have been clearly identified for Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome? (Etiology)

The exact underlying cause of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome is currently unknown.

What are the Signs and Symptoms of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome?

The signs and symptoms of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome may include:

• Intra-uterine growth retardation (IUGR), which may be mild
• Cleft lower lip
• Thick, short tongue
• Presence of teeth at birth
• Retinal detachment, which may occur in one eye
• Degeneration of retinal tissue may occur in the eye without retinal detachment

How is Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome Diagnosed?

Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome is diagnosed on the basis of the following information:

• Complete physical examination
• Thorough medical history evaluation
• Assessment of signs and symptoms
• Laboratory tests
• Imaging studies
• Biopsy studies, if necessary

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome?

The complications of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome may include:

• Inability to feed properly owing to tongue-tie and cleft lip
• Speech impediment
• Visual impairment
• Low self esteem

Complications may occur with or without treatment, and in some cases, due to treatment also.

How is Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome Treated?

There is no cure for Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome. The treatment is usually given to manage the signs and symptoms and any complication that develops.

How can Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome be Prevented?

• Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome may not be preventable, since it is a congenital disorder with no identified risk factor
• Regular medical screening at periodic intervals with tests and physical examinations are recommended

What is the Prognosis of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome? (Outcomes/Resolutions)

• The prognosis of Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome is dependent upon the severity of the signs and symptoms and associated complications, if any
• Individuals with mild conditions have better prognosis than those with severe symptoms and complications
• Typically, the prognosis may be assessed on a case-by-case basis

Additional and Relevant Useful Information for Cleft Lower Lip Cleft Lateral Canthi Chorioretinal Syndrome:

The following DoveMed website link is a useful resource for additional information:

http://www.dovemed.com/diseases-conditions/rare-disorders/