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Calcifying Aponeurotic Fibroma

Last updated Jan. 24, 2022

Reviewed by: Lester Fahrner, MD

Approved by: Krish Tangella MD, MBA, FCAP


Microscopic pathology image showing a benign calcifying aponeurotic fibroma.

What are the other Names for this Condition? (Also known as/Synonyms)

  • Calcifying Juvenile Aponeurotic Fibroma
  • Juvenile Aponeurotic Fibromatosis
  • Juvenile Nodular Aponeurotic Fibroma

What is Calcifying Aponeurotic Fibroma? (Definition/Background Information)

  • Calcifying Aponeurotic Fibroma is a rare, painless, and slow-growing tumor mass. The tumors do not tend to metastasize
  • This tumor nodule is attached to a tendon or a fascia and are generally seen on the hands and legs
  • A tissue biopsy helps in a definitive diagnosis of the condition, which is treated through a surgical removal of the tumor. This may result in a cure, although recurrence of the condition is high, especially in children
  • The occurrence of Calcifying Aponeurotic Fibroma may not be prevented. Nevertheless, the prognosis on appropriate treatment is good

Who gets Calcifying Aponeurotic Fibroma? (Age and Sex Distribution)

  • Calcifying Aponeurotic Fibroma may occur in individuals of all races, ethnic groups, and gender
  • Children and young individuals are affected the most. Hence, it is also called Juvenile Aponeurotic Fibroma (JAF)

What are the Risk Factors for Calcifying Aponeurotic Fibroma? (Predisposing Factors)

  • The risk factors of Calcifying Aponeurotic Fibroma are unknown

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases ones chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Calcifying Aponeurotic Fibroma? (Etiology)

The cause of Calcifying Aponeurotic Fibroma formation is presently unknown.

What are the Signs and Symptoms of Calcifying Aponeurotic Fibroma?

The signs and symptoms of Calcifying Aponeurotic Fibroma may include:

  • Swollen mass of the tumor, usually seen on the hands and feet
  • Generally, the tumors are less than 3cm in dimension

How is Calcifying Aponeurotic Fibroma Diagnosed?

Calcifying Aponeurotic Fibroma diagnosis involves:

  • Physical examination and evaluation of complete medical history
  • Radiological studies, such as X-ray of the affected region and MRI and CT scan of the affected region. Such studies may show areas of calcification (hence, the term ‘calcifying’)
  • A tissue biopsy, where the tissue is examined by a pathologist under the microscope, to arrive at a definitive diagnosis

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Calcifying Aponeurotic Fibroma?

The possible complications from Calcifying Aponeurotic Fibroma include:

  • Over 50% of tumors recur after surgical excision; the risk of such a recurrence is higher in children
  • The tumor size and resulting pain or disability with movement may affect the quality of one’s life

How is Calcifying Aponeurotic Fibroma Treated?

Treatment of Calcifying Aponeurotic Fibroma is a complete surgical excision, which results in a cure. However, the recurrence risk of the condition remains high, particularly among children.

How can Calcifying Aponeurotic Fibroma be Prevented?

Calcifying Aponeurotic Fibroma benign tumor condition may not be preventable, as the cause and risk factors are presently unknown.

What is the Prognosis of Calcifying Aponeurotic Fibroma? (Outcomes/Resolutions)

The prognosis of Calcifying Aponeurotic Fibroma is generally good with adequate treatment.

Additional and Relevant Useful Information for Calcifying Aponeurotic Fibroma:

The following DoveMed website link is a useful resource for additional information:


What are some Useful Resources for Additional Information?

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Reviewed and Approved by a member of the DoveMed Editorial Board
First uploaded: May 12, 2014
Last updated: Jan. 24, 2022