Annular Subacute Cutaneous Lupus Erythematosus

Annular Subacute Cutaneous Lupus Erythematosus

Article
Skin Care
Women's Health
+3
Contributed byLester Fahrner, MD+1 moreAug 14, 2023

What are the other Names for this Condition? (Also known as/Synonyms)

  • Annular SCLE
  • Subacute Cutaneous Lupus Erythematosus, Annular subtype

What is Annular Subacute Cutaneous Lupus Erythematosus? (Definition/Background Information)

  • Annular Subacute Cutaneous Lupus Erythematosus is a subtype of subacute cutaneous lupus erythematosus (SCLE). It presents with characteristic annular (ring-shaped) skin lesions that are photosensitive and may resemble other skin conditions
  • The risk factors for the condition are not clearly understood, but the cause may be related to a dysfunctional immune system in certain individuals. Annular Subacute Cutaneous Lupus Erythematosus is mostly seen in young and middle-aged women
  • The treatment for this form of SCLE may involve topical and systemic medications, including avoiding sun exposure. With adequate management of Annular Subacute Cutaneous Lupus Erythematosus, the outcomes are generally good

Who gets Annular Subacute Cutaneous Lupus Erythematosus? (Age and Sex Distribution)

  • Annular Subacute Cutaneous Lupus Erythematosus can occur at any age
  • But it is more commonly observed in young to middle-aged adults, especially women
  • Worldwide, no particular race or ethnicity preference is observed

What are the Risk Factors for Annular Subacute Cutaneous Lupus Erythematosus? (Predisposing Factors)

  • The exact risk factors for Annular Subacute Cutaneous Lupus Erythematosus are not well-defined
  • It is believed to be associated with a genetic predisposition and triggered by factors such as sunlight and certain medications

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Annular Subacute Cutaneous Lupus Erythematosus? (Etiology)

  • The underlying cause of Annular Subacute Cutaneous Lupus Erythematosus is related to the immune system's abnormal response in individuals with genetic susceptibility
  • Environmental triggers, such as ultraviolet (UV) light exposure and certain medications, may contribute to disease development

What are the Signs and Symptoms of Annular Subacute Cutaneous Lupus Erythematosus?

The signs and symptoms of Annular Subacute Cutaneous Lupus Erythematosus may include:

  • Annular (ring-shaped) or psoriasiform (psoriasis-like) skin lesions
  • Lesions are typically red, raised, and scaly
  • Lesions may appear on sun-exposed areas like the arms, chest, and back
  • Photosensitivity, where skin worsens with sun exposure
  • Itchiness and pain in the affected areas

How is Annular Subacute Cutaneous Lupus Erythematosus Diagnosed?

A diagnosis of Annular Subacute Cutaneous Lupus Erythematosus may involve:

  • Physical exam, clinical evaluation of symptoms, and medical history
  • Blood tests to detect specific autoantibodies and assess organ function
  • Skin biopsy for microscopic examination of affected tissue

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Annular Subacute Cutaneous Lupus Erythematosus?

Complications of Annular Subacute Cutaneous Lupus Erythematosus may include the development of systemic lupus erythematosus (SLE) in some individuals.

How is Annular Subacute Cutaneous Lupus Erythematosus Treated?

The treatment of Annular Subacute Cutaneous Lupus Erythematosus may involve:

  • Topical corticosteroids to reduce inflammation and relieve symptoms
  • Antimalarial medications to manage skin lesions and prevent disease progression
  • Avoiding sun exposure and using sun protection measures
  • Systemic medications for more severe cases

How can Annular Subacute Cutaneous Lupus Erythematosus be Prevented?

There is no specific way to prevent Annular Subacute Cutaneous Lupus Erythematosus, but managing sun exposure and avoiding triggering medications may help reduce flares.

What is the Prognosis of Annular Subacute Cutaneous Lupus Erythematosus? (Outcomes/Resolutions)

  • The prognosis of Annular Subacute Cutaneous Lupus Erythematosus varies based on individual cases
  • With appropriate treatment and sun protection, many patients can achieve remission and effectively manage their symptoms

Additional and Relevant Useful Information for Annular Subacute Cutaneous Lupus Erythematosus:

  • Cutaneous lupus erythematosus (CLE) constitutes a wide group of autoimmune disorders primarily affecting the skin. It may or may not be associated with systemic lupus erythematosus (SLE), which may cause systemic symptoms involving the entire body and several important organs

Read more about the condition at the following link:

https://www.dovemed.com/diseases-conditions/cutaneous-lupus-erythematosus/

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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