What are the other Names for this Condition? (Also known as/Synonyms)

• Acne Telangiectoides of Kaposi
• Facial Idiopathic Granulomas with Regressive Evolution (FIGURE)
• Lupus Miliaris Disseminatus Faciei (LMDF)

What is Acne Agminata? (Definition/Background Information)

• Acne Agminata (AA) is a rare skin condition often observed in young adults, which is marked by numerous tiny acne-like superficial skin lesions clustered together (agminated) on the face. The condition is also known as Lupus Miliaris Disseminatus Faciei (LMDF)
• The cause of occurrence and predisposing factors for Acne Agminata are presently unknown. Following a diagnosis of the condition, it may be treated using topical and systemic medications. With adequate treatment, the prognosis of Acne Agminata may be good

Who gets Acne Agminata? (Age and Sex Distribution)

• Acne Agminata is generally observed in young adults, even though individuals of a broader age group (children and older adults) may be affected
• Both males and females are affected, and no gender preference is noted
• Worldwide, there is no racial or ethnic preference observed

What are the Risk Factors for Acne Agminata? (Predisposing Factors)

• The risk factors for Acne Agminata are currently unidentified

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Acne Agminata? (Etiology)

• Currently, the cause of occurrence of Acne Agminata (AA) is not well-understood
• According to medical literature, AA is not an infectious disease
• Despite the “acne” name associated with it, AA is not likely of the same disease family as acne

The condition does not spread from one individual to another through physical contact or through sharing of items since it is a non-infectious condition.

What are the Signs and Symptoms of Acne Agminata?

The signs and symptoms of Acne Agminata may include:

• Presence of numerous small red-brown-yellow raised skin lesions
• The lesions are in the form of papules (raised bumps) and pustules (pus-filled papules)
• The skin eruptions are predominantly observed on the face, including on the cheeks, chin, forehead, around the eyes, and on the eyelids
• Rarely, the lesions are observed on the armpits (axilla)
• Pain, irritation, and discomfort may be felt

How is Acne Agminata Diagnosed?

A diagnosis of Acne Agminata may involve the following exams and procedures:

• Physical examination of the individual and medical history evaluation. In many cases, a dermatologist can diagnose Acne Agminata following a visual examination of the condition and via an assessment of the presenting signs and symptoms
• Blood tests, analysis of pus, and culture of the fluid being drained (for causative pathogen), as needed
• Dermoscopy: Dermoscopy is a diagnostic tool where a dermatologist examines the skin using a special magnified lens
• Wood’s lamp examination: In this procedure, the healthcare provider examines the skin using ultraviolet light. It is performed to examine the change in skin pigmentation
• Skin biopsy: A skin tissue biopsy is performed and sent to a laboratory for a pathological examination. The pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed), and microscope findings, the pathologist arrives at a definitive diagnosis

A differential diagnosis is important to exclude other conditions/infections that present similar signs and symptoms. These may include:

• Acne vulgaris
• Cutaneous leishmaniasis
• Cutaneous mycobacterial infection, including tuberculosis
• Granuloma annulare
• Rosacea
• Sarcoidosis

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Acne Agminata?

The possible complications due to Acne Agminata include:

• Emotional and psychological stress
• Cosmetic issues
• Superimposed bacterial and fungal skin infections
• Permanent scarring on healing if appropriate treatment is not provided
• Persistence of acne-like skin lesions for many years
• Treatment complications

How is Acne Agminata Treated?

There are no well-defined treatment measures available for Acne Agminata. The healthcare provider may manage the condition using the following treatments:

• Application of topical antibacterial creams
• Oral antibiotics
• Use of topical retinoids
• Topical and oral corticosteroids

Regular follow-up visits with the healthcare provider is important and recommended.

Self-care (home) remedies may include:

• Wash the lesions with mild (antibacterial) soap
• Apply a warm compress
• Wash hands before applying topical applications
• Keep nails trimmed, and do not pick at the scalp lesions

How can Acne Agminata be Prevented?

Presently, it may not be possible to prevent Acne Agminata since the cause of the condition is unknown. However, the following measures may be considered:

• Maintain good personal hygiene
• Limit sun exposure, especially on the face
• Minimize the use of any cosmetic products
• Avoid community swimming pools

What is the Prognosis of Acne Agminata? (Outcomes/Resolutions)

• The prognosis of Acne Agminata (AA) is generally good with adequate treatment
• However, in the absence of adequate treatment, AA may persist for a few years and heal with scarring

Additional and Relevant Useful Information for Acne Agminata:

The following DoveMed website link is a useful resource for additional information:

https://www.dovemed.com/healthy-living/skin-disorders/