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Working Memory In Aging Adults Becomes Increasingly Affected By Alcohol

Last updated Aug. 17, 2016

Approved by: Maulik P. Purohit MD, MPH

Jez Timms

Working memory can be thought of as short-term memory, temporarily holding ideas and recent events in the mind for quick recall. Working memory often declines with age; it may also be susceptible to interactions between age and alcohol use.


Working memory can be thought of as short-term memory, temporarily holding ideas and recent events in the mind for quick recall. Working memory often declines with age; it may also be susceptible to interactions between age and alcohol use. Frontal theta power (FTP) and posterior alpha power (PAP) are electrophysiological measures of brain activity associated with cognitive effort and maintenance of visual information. This study looks at alcohol effects on FTP and PAP during a working memory task in younger and older social drinkers.

Researchers recruited two groups of participants for this study: 51 older (55-70 years of age; 29 women, 22 men), and 70 younger (25-35 years of age; 39 women, 31 men) moderate drinkers living in the community. Participants were given either a placebo or an active dose designed to produce a breath alcohol concentration of 0.04 or 0.065 g/dL. Following absorption, participants completed a visual working-memory task in which they were required to remember briefly-shown images during a nine-second delay period. FTP and PAP were recorded during this delay.

During working memory maintenance, PAP was lower in the older than the younger adults. In addition, active alcohol doses increased PAP in younger adults but decreased PAP in older adults. These results support a small but growing body of evidence that older adults are more sensitive than younger adults to the neurobehavioral effects of moderate alcohol use, and further demonstrate that PAP activity may help to identify alcohol's negative effects on working-memory efficiency in older adults.


The above post is reprinted from materials provided by Research Society on AlcoholismNote: Content may be edited for style and length.

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Primary Resource:

Boissoneault, J., Frazier, I., Lewis, B., & Nixon, S. J. (2016). Effects of Age and Acute Moderate Alcohol Administration on Electrophysiological Correlates of Working Memory Maintenance. Alcoholism: Clinical and Experimental Research.

Reviewed and Approved by a member of the DoveMed Editorial Board
First uploaded: Aug. 17, 2016
Last updated: Aug. 17, 2016