Physical Activity May Ward Off Heart Damage

Physical Activity May Ward Off Heart Damage

ArticlePress release
Bone, Muscle, & Joint
Heart & Vascular Health
+2
Contributed byKrish Tangella MD, MBAMay 08, 2017

Physical activity can lower the risk of heart damage in middle-aged and older adults and reduce the levels of heart damage in people who are obese, according to research published in JACC: Heart Failure.

Obesity is associated with structural and functional abnormalities in the heart and subsequent heart failure. Heart failure may be caused by subclinical myocardial damage, in which there is damage to the heart muscle but a patient does not show sign or symptoms.

Researchers examined 9,427 patients aged 45-64 years without cardiovascular disease and a body mass index of more than 18.5 kg/m2. Physical activity was measured through a questionnaire and categorized according to current guidelines as "recommended" (at least 75 minutes per week of vigorous intensity or at least 150 minutes per week of a combination of moderate to vigorous intensity), "intermediate" (1-74 minutes per week of vigorous intensity or 1-149 minutes of a combination of moderate to vigorous intensity), or "poor" (no moderate to vigorous exercise). To measure damage to the heart, researchers assessed levels of high sensitivity troponin T. Elevated levels of this biomarker are considered a marker of heart damage and have been shown to be associated with future heart failure.

Elevated levels of high sensitivity troponin T were observed in 7.2 percent of the total study population. Individuals with lower levels of physical activity were significantly more likely to have elevated levels of high sensitivity troponin suggesting higher heart damage. For example, participants who performed poor and intermediate levels of physical activity were 39 percent and 34 percent more likely to have heart damage than persons who engaged in recommended levels of physical activity.

The researchers subsequently looked at the combined associations of physical activity and obesity with this blood marker of heart damage. Obesity had been previously shown to be strongly associated with elevated levels of high sensitivity troponin, and the combination of obesity and elevated troponin was associated with a significantly increased risk of future heart failure. In the current study, the authors demonstrated that participants with obesity who performed poor levels of exercise had the highest likelihood of having elevated high sensitivity troponin levels. Participants with obesity who performed recommended levels of physical activity had a weaker association with elevated levels of high sensitivity troponin, and after adjustment for traditional cardiac risk factors, this was association was no longer statistically significant. These results suggest physical activity may lessen the association of obesity and heart damage. The authors also found a significant interaction between physical activity and obesity on elevated levels of high sensitivity troponin, which indicates that the protective association of physical activity and heart damage may be stronger among individuals with obesity, a group at particularly high risk for future heart failure.

"The protective association of physical activity against subclinical myocardial damage may have implication for heart failure risk reduction, particularly among the high-risk group of individuals with excess weight," said Roberta Florido, MD, cardiology fellow at Johns Hopkins Hospital and lead author of the study. "Promoting physical activity may be a particularly important strategy for heart failure risk reductions among high risk groups such as those with obesity."

In an accompanying editorial comment, Tariq Ahmad, MD, MPH, FACC, and Jeffrey M. Testani, MD, MTR, said they encourage cardiologists to promote healthy habits rather than simply treating heart failure after it has developed.

"In this report we add to the body of evidence supporting moderate physical activity and its protective effect in the setting of obesity," said JACC: Heart Failure Editor-in-Chief Christopher O'Connor, MD, FACC.


Materials provided by American College of CardiologyNote: Content may be edited for style and length.

Disclaimer: DoveMed is not responsible for the accuracy of the adapted version of news releases posted to DoveMed by contributing universities and institutions.

Primary Resource:

Florido, R., Ndumele, C. E., Kwak, L., Pang, Y., Matsushita, K., Schrack, J. A., ... & Coresh, J. (2017). Physical activity, obesity, and subclinical myocardial damage. JACC: Heart Failure5(5), 377-384. DOI: 10.1016/j.jchf.2017.02.002

Was this article helpful

On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

0 Comments

Please log in to post a comment.

Related Articles

Test Your Knowledge

Asked by users

Related Centers

Loading

Related Specialties

Loading card

Related Physicians

Related Procedures

Related Resources

Join DoveHubs

and connect with fellow professionals

Related Directories

Who we are

At DoveMed, our utmost priority is your well-being. We are an online medical resource dedicated to providing you with accurate and up-to-date information on a wide range of medical topics. But we're more than just an information hub - we genuinely care about your health journey. That's why we offer a variety of products tailored for both healthcare consumers and professionals, because we believe in empowering everyone involved in the care process.
Our mission is to create a user-friendly healthcare technology portal that helps you make better decisions about your overall health and well-being. We understand that navigating the complexities of healthcare can be overwhelming, so we strive to be a reliable and compassionate companion on your path to wellness.
As an impartial and trusted online resource, we connect healthcare seekers, physicians, and hospitals in a marketplace that promotes a higher quality, easy-to-use healthcare experience. You can trust that our content is unbiased and impartial, as it is trusted by physicians, researchers, and university professors around the globe. Importantly, we are not influenced or owned by any pharmaceutical, medical, or media companies. At DoveMed, we are a group of passionate individuals who deeply care about improving health and wellness for people everywhere. Your well-being is at the heart of everything we do.

© 2023 DoveMed. All rights reserved. It is not the intention of DoveMed to provide specific medical advice. DoveMed urges its users to consult a qualified healthcare professional for diagnosis and answers to their personal medical questions. Always call 911 (or your local emergency number) if you have a medical emergency!