Worldwide, the incidence of tuberculosis (TB) has declined by over 30% since 1990; however, TB in India is prevalent and on the rise. The alarming news is that it is not the type of TB that can be successfully treated with antibiotics, but rather it is a Multidrug-Resistant (MDR) TB form, which is more difficult to eliminate with current antibiotics.
In most cases, TB is caused by a bacterium called Mycobacterium tuberculosis. These bacteria usually attack the lungs, but could potentially infect other organs as well. Individuals diagnosed with TB should normally undergo treatment for several months with different medicines until the infection is completely removed.
Why are TB and MDR TB on the rise?
o The lack of well-qualified and accredited laboratories.
o The slow diagnostic tools - TB patients can spread the disease during this time, and MDR TB patients can die before given the appropriate treatment.
o Insufficient treatment management.
o Scarcity in medicine - MDR TB treatments are more toxic, expensive, and extensive.
o A shortage of trained medical workers.
o Unavailability of equipment to test for TB drug resistance.
o Infected patients having short hospitalizations due to their unwillingness to stay isolated for more than a week.
Why the increase in MDR TB?
There are several probable contributing factors to the rise of the drug-resistant form of TB:
o When a bacterial population is exposed to antibiotics, some of them can survive and grow. This is normal, but the rate at which it occurs can be exacerbated by improper treatment, misuse, and mismanagement.
o Private clinics in India typically do not employ appropriate treatment. regimens, which may be placing selective pressure on the TB causing bacterial species
What is being done to stop it?
Extensively drug-resistant TB (XDR TB) is now surfacing in India, along with an incurable form of TB. Thus, in order to decrease the prevalence of TB and MDR TB, it is vital that the Indian authorities understand the seriousness of the matter. Immediate steps should be taken to curb the spread of the disease.
Written by Monique Richards
References
Tuberculosis (TB). Retrieved from http://www.cdc.gov/tb/
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Steinbrook, R. (2007). Tuberculosis and HIV in India. The New England Journal of Medicine, 356, pp. 1198-1198. Retrieved from http://www.nejm.org/doi/full/10.1056/NEJMp078049
(2012). Facing the Reality of Drug-Resistant Tuberculosis in India: Challenges and Potential Solutions: Summary of a Joint Workshop by the Institute of Medicine, the Indian National Science Academy, and the Indian Council of Medical Research. Washington (DC): National Academies Press. Retrieved from http://www.ncbi.nlm.nih.gov/books/NBK100386/
Rowland, Katherine. (2012 Jan 13). Totally drug-resistant TB emerges in India. Retrieved from http://www.nature.com/news/totally-drug-resistant-tb-emerges-in-india-1.9797
Suen, S., Bendavid, E. & Goldhaber-Fiebert, J. D. (2014 Mar 7). Disease Control Implications of India’s Changing Multi-Drug Resistant Tuberculosis Epidemic. PLOS One, 9(3), pp. 1-11. Retrieved from http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089822
What is the relationship between TB and poverty. Retrieved from http://www.stoptb.org/assets/documents/events/world_tb_day/2002/1Therelationship.pdf
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