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First Skin-To-Eye Stem Cell Transplant In Humans Successful

Last updated May 20, 2016

Approved by: Krish Tangella MD, MBA, FCAP

Macular Degeneration is a disease which affects the retina. DoveMed has found this great video that describes the symptoms of Macular Degeneration.


Researchers have safely transplanted stem cells derived from a patient's skin to the back of the eye in an effort to restore vision. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Seattle, Wash.

A small piece of skin from the patient's arm was collected and modified into induced pluripotent stem cells (iPSC). The iPSCs were then transformed into eye cells, which were transplanted into the patient's eye. The transplanted cells survived without any adverse events for over a year and resulted in slightly improved vision.

The patient suffered from advanced wet age-related macular degeneration (AMD) that did not respond to current standard treatments.

iPSCs are adult cells that have been reprogrammed to an embryonic stem cell-like state, which can then be differentiated into any cell type found in the body.

Abstract Title: Transplantation of Autologous induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets for Exudative Age Related Macular Degeneration: A Pilot Clinical Study



The above post is reprinted from materials provided by Association for Research in Vision and Ophthalmology (ARVO)Note: Materials may be edited for content and length.

Disclaimer: DoveMed is not responsible for the adapted accuracy of news releases posted to DoveMed by contributing universities and institutions.

Primary Resource:

Ruddock, H. K., Christiansen, P., Jones, A., Robinson, E., Field, M., & Hardman, C. A. (2016). Believing in food addiction: Helpful or counterproductive for eating behavior?. Obesity.

Reviewed and Approved by a member of the DoveMed Editorial Board
First uploaded: May 20, 2016
Last updated: May 20, 2016