Two main methods are used to test for infection:
The healthcare provider may order Chickenpox and Shingles Test in the following cases:
Individuals in the following category should also get tested:
Sample required: Blood for VZV antibody testing; body fluids to detect the virus
Process: Insertion of needle into a vein (arm) to obtain blood sample. Fluid is collected from a blister, cerebrospinal fluid, or other body fluids
Preparation required: None
The significance of Chickenpox and Shingles Test results are explained below:
Presence of both IgG and IgM:
Presence of IgM:
Sometimes, an individual showing typical signs and symptoms may have low or undetectable levels of IgG and/or IgM. This is an indication that the person may either have a condition other than VZV, or that the individual’s immunity is compromised. The immune system may not be responding normally, and is thus unable to produce enough antibodies to fight the infection.
Detection of VZV virus through viral cultures, viral DNA analysis, or direct fluorescent antibody tests, confirms the presence of infection. However, a negative test result may either be due to the absence of or the presence of low numbers, of the viral particles in the sample. Thus, a negative test result may not indicate an absence of infection.
The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. The test results have to be interpreted after correlating with suitable clinical findings and additional supplemental tests/information. Your healthcare providers will explain the meaning of your tests results, based on the overall clinical scenario.
Chickenpox:
Shingles (or Herpes Zoster):
IgM & IgG antibodies:
Certain medications that you may be currently taking may influence the outcome of the test. Hence, it is important to inform your healthcare provider, the complete list of medications (including any herbal supplements) you are currently taking. This will help the healthcare provider interpret your test results more accurately and avoid unnecessary chances of a misdiagnosis.
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