Verruga Peruana

Verruga Peruana

Article
Brain & Nerve
Digestive Health
+8
Contributed byKrish Tangella MD, MBAOct 27, 2022

The topic Verruga Peruana you are seeking is a synonym, or alternative name, or is closely related to the medical condition Carrion’s Disease.

Quick Summary:

  • Carrion’s Disease is a bacterial illness endemic to the Andes Mountains in Western South America including Peru, Colombia, and Ecuador. It is caused by the bacterium Bartonella bacilliformis, which is transmitted through the bites of sandflies belonging to the genus Lutzomyia
  • Carrion’s Disease is a biphasic illness with two distinct phases:
    • The acute phase is classically known as “Oroya Fever”. It occurs mostly in immunologically naive individuals; meaning that they have been exposed to the infection for the first time and their immune system is new to the infection. It is characterized by fever and hemolytic anemia. If not timely treated with antibiotics, Oroya Fever can lead to severe life-threatening complications
    • The chronic phase is the eruptive phase, classically known as “Verruga Peruana”. It is characterized by nodular skin lesions which are highly vascular and may bleed on touch. It is a benign condition which resolves in 3-6 months even without treatment. Verruga Peruana occurs in previously infected individuals, who may or may not have had an antecedent acute febrile illness
  • The bacterium circulates in the blood of all patients during the acute phase. Therefore, the acute phase is most commonly diagnosed by direct observation of the bacteria in peripheral blood smears or culturing it from blood. The eruptive phase is diagnosed by histopathological examination of biopsy samples from the skin lesions
  • There are highly effective antibiotics available for the treatment of Carrion’s Disease. However, the treatment requires prolonged courses of antibiotics, which can lead to the emergence of antibiotic resistance and several other side effects. Therefore, antibiotics should not be taken without the advice of a healthcare professional, and it is important to consult an infectious disease expert regarding antibiotic options
  • Currently, there is no vaccine available for preventing Carrion’s Disease. Untreated individuals with the acute phase of disease have high mortality rates. A very small percentage of individuals develop the chronic phase; the lesions of which typically heal over several months with adequate treatment

Please find comprehensive information on Carrion’s Disease regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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