Tree Man Syndrome

Tree Man Syndrome

Article
Skin Care
Diseases & Conditions
+3
Contributed byLester Fahrner, MD+1 moreAug 24, 2021

The topic Tree Man Syndrome you are seeking is a synonym, or alternative name, or is closely related to the medical condition Epidermodysplasia Verruciformis.

Quick Summary:

  • Epidermodysplasia Verruciformis (EV) is a rare skin disorder, characterized by wart-like lesions on the skin that are caused by repeated and chronic infection with human papillomavirus (HPV). The chronic HPV infection occurs because of increased susceptibility to the virus, due to genetic mutations or reduced immunity
  • The affected individuals develop warts, in small groups or clusters made up of numerous scaly structures, which resemble a tree bark. Hence, the condition is also known as Tree Man Syndrome
  • Epidermodysplasia Verruciformis can either be inherited or acquired; the latter caused by suppression of immunity owing to medications, or human immunodeficiency virus (HIV) infection. When the cause is genetic, mutation(s) in the EVER1 and EVER2 genes on chromosome 17 may result in the disorder
  • The diagnosis of Epidermodysplasia Verruciformis may involve clinical observations and immunohistochemical studies. Untreated or inadequately treated skin lesions may turn cancerous, generally to squamous cell carcinoma or intra-epidermal carcinoma (non-melanoma skin cancers)
  • Epidermodysplasia Verruciformis disorder is managed with retinoid treatments, cryotherapy, and surgical excision of the warts. The outcome, in most cases, is typically favorable with effective treatment

Please find comprehensive information on Epidermodysplasia Verruciformis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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