The topic Testicular Mixed Germ Cell Tumor you are seeking is a synonym, or alternative name, or is closely related to the medical condition Mixed Germ Cell Tumor of the Testis.

Quick Summary:

• Mixed Germ Cell Tumor of the Testis is a type of testicular cancer affecting the germ cells. Germ cells are precursors to sperm cells that will eventually transform into sperms
• The testes are the male reproductive organs, equivalent to the ovaries in women. They are housed in the scrotum; the sac-like structure in the groin. The testis have 2 main functions:
  • Male hormone production
  • Sperm production         
• Testicular cancer is cancer of the testicle, or testis. It is the most common form of cancer in young men aged 15-35 years. It is generally aggressive, but treatable when identified early
• More than 90% of testicular cancers arise from abnormalities in the germ cells. Germ cells are one of the two types of cells in the body. They form sex cells - the sperms and eggs, while the other type, somatic cells, forms everything else (all other body organs and parts)
• Normal germ cells arise from pluripotent stem cells. Pluripotent stem cells can differentiate into, or become, any cell in the body. Thus, pluripotent stem cells may become either germ cells or somatic cells
• The process of pluripotent stem cells becoming other cell types is mediated by chemical signaling. Chemicals that act as signals include growth factors, nutrients, and hormones
• Stem cells that do not respond to normal signals may grow uncontrollably and cause tumors. This tumor-causing potential makes them “neoplastic”. Neoplastic cells that grow aggressively and spread to other areas are cancerous
• There are two types of testicular germ cell cancer:
  • Seminoma: It is a slow-growing cancer affecting men in their 30s and 40s, which is usually confined to the testis. These are of 2 types - classical and spermatocytic seminoma
  • Nonseminoma: It is a fast-growing cancer affecting males in their late teens through 30s, which aggressively metastasizes, or spreads. These are of 4 types - embryonal carcinoma, yolk sac carcinoma, choriocarcinoma, and teratoma          
• Mixed Germ Cell Tumor of the Testis is made up of 2 or more different types of germ cell tumors; those that are both seminomas and nonseminomas. However, they grow and spread like nonseminomas, and for this reason, they are treated as nonseminomas. The cause of Mixed Germ Cell Tumor of the Testis is unknown
• Mixed Germ Cell Tumor of the Testis make up for 15% of all germ cell tumors. But, because germ cell tumors make up 90% of all testicular cancers, this is equivalent to stating that this tumor type makes up for 10% of all testicular cancers

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