Simmonds’ Syndrome

Simmonds’ Syndrome

Article
Brain & Nerve
Diseases & Conditions
+1
Contributed byKrish Tangella MD, MBAApr 03, 2018

The topic Simmonds’ Syndrome you are seeking is a synonym, or alternative name, or is closely related to the medical condition Sheehan Syndrome.

Quick Summary:

  • Sheehan Syndrome is decreased functioning of pituitary gland, caused by damage to the gland from severe blood loss during or after childbirth. It is a rare complication of pregnancy
  • The pituitary gland is a very small gland in the brain, which secretes many essential hormones. When the pituitary gland damage is unrelated to pregnancy, the condition is called Simmonds’ Syndrome
  • It is believed by the medical community that 75-90% damage to the anterior pituitary gland is a pre-requisite for Sheehan Syndrome to set in and for the symptoms to show
  • Although the exact cause of maternal bleeding is not known, it is believed that the enlarged size of the pituitary gland during pregnancy necessitates increased oxygen demand, and any shortage therefore, predisposes it to damage
  • Excessive bleeding and resultant drop in blood pressure damage the pituitary gland. Rarely, damage to the pituitary gland may also be observed with some other conditions such as sickle cell anemia
  • The symptoms of Sheehan Syndrome are dictated by the extent of damage to the pituitary gland, and consequent hormonal imbalance. Some typical symptoms include inability to breastfeed the baby, constipation, and reduced mental acuity
  • A healthcare provider might use symptoms’ assessment, medical history, along with blood test and/or imaging scans to arrive at an accurate diagnosis
  • Standard treatment options for Sheehan Syndrome include hormonal treatment to compensate for loss of pituitary function. The treatment is often required lifelong. If not diagnosed and treated promptly, Sheehan Syndrome could be fatal
  • Sheehan Syndrome may be preventable if a healthcare provider is vigilant during childbirth and proper medical care for excessive bleeding is rendered. With an early diagnosis and prompt treatment, the prognosis for the condition is reported to be excellent

Please find comprehensive information on Sheehan Syndrome regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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