Silver-Russell Syndrome (SRS)

Silver-Russell Syndrome (SRS)

Article
Ear, Nose, & Throat (ENT)
Dental Health
+3
Contributed byMaulik P. Purohit MD MPHNov 05, 2020

The topic Silver-Russell Syndrome (SRS) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Russell-Silver Syndrome.

Quick Summary:

  • Russell-Silver Syndrome (RSS) is a prenatal and post-birth growth disorder characterized by stunted appearance, a disproportionately large head, triangular face and abnormalities involving various organ systems in the body
  • RSS is one of the 200 types of dwarfism and one of the five types of primordial dwarfism that is recorded in the medical literature. It is an extremely rare disorder
  • Russell-Silver Syndrome is known as an “imprinting disorder”. Imprinting is a chemical process of silencing gene expression. The genetic causes for RSS are complex, predominantly involving chromosomes 7 and 11. The risk factors for the disorder are also not clear, since most of the cases occur spontaneously
  • Aside from routine tests, growth hormone measurements and chromosome testing may be used to establish a diagnosis of Russell-Silver Syndrome
  • Specialists from various medical fields, such as pediatricians, endocrinologists, dentists, and physiotherapists, are often needed for the treatment of RSS. Even though incurable, individuals with Russell-Silver Syndrome are reported to have a normal life expectancy

Please find comprehensive information on Russell-Silver Syndrome regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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