Severe Muscle Pain and Abnormally High Eosinophils

Severe Muscle Pain and Abnormally High Eosinophils

Article
Brain & Nerve
Bone, Muscle, & Joint
+5
Contributed byKrish Tangella MD, MBAMay 14, 2020

The topic Severe Muscle Pain and Abnormally High Eosinophils you are seeking is a synonym, or alternative name, or is closely related to the medical condition Eosinophilia-Myalgia Syndrome.

Quick Summary:

  • Eosinophilia-Myalgia Syndrome (EMS) is a rare and unique disorder characterized by flu-like symptoms and elevated eosinophils (type of white blood cells) in blood. It is caused by the consumption of certain supplements including L-tryptophan and 5-hydroxytryptophan
  • EMS was an epidemic that surfaced in the late 1980’s and early 1990’s from the use of contaminated L-tryptophan; but since then, there have been very few isolated cases of the syndrome reported worldwide. The condition was controlled through regulatory measures and drug recalls following its recognition
  • Eosinophilia-Myalgia Syndrome can affect several body organs including the muscular system, gastrointestinal system, respiratory system, and cutaneous system, resulting in severe complications. EMS was commonly described among European and American Caucasian women (during the time of the outbreak)
  • The signs and symptoms of Eosinophilia-Myalgia Syndrome that may be acute or chronic may include muscle pain, shortness of breath, skin rashes, hair loss, behavioral issues, and dulled cognitive function. If left untreated, EMS may lead to compromised liver function, heart-lung disease, and depression
  • Often, symptomatic treatment is provided, which may involve the administration of pain medication, muscle relaxants, and corticosteroid drugs, apart from discontinuing use of the offending supplement. In a vast majority, the prognosis of Eosinophilia-Myalgia Syndrome is good; however, this also depends upon the severity of the condition

Please find comprehensive information on Eosinophilia-Myalgia Syndrome regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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