The topic Reactive Large Granular Lymphocytosis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Transient Large Granular Lymphocytosis.

Quick Summary:

• Transient Large Granular Lymphocytosis is a short-term increase in large granular lymphocyte numbers (usually less than 6 months) that may be seen in association with a variety of conditions including viral infections, autoimmune disorders, and non-lymphoid malignancies
• Large granular lymphocytes (LGLs) are present in peripheral blood in normal adults. The LGLs usually constitute 10-15% of the mononuclear cells in peripheral blood and they fight infections. The term “lymphocytosis” indicates an increased number of lymphocytes in peripheral blood
• In Transient Large Granular Lymphocytosis, the increase is usually reactive in nature and non-malignant. Such short-term increase should not be misdiagnosed as LGL leukemias (that are types of blood cancers)
• However, if there are persistent increases in LGLs, diagnostic work-ups or additional studies should be performed to rule out a large granular lymphocyte leukemia (LGLL)
• Transient Large Granular Lymphocytosis may or may not present with any significant symptoms. However, the signs and symptoms of the underlying condition may be observed
• Individuals with Transient Large Granular Lymphocytosis are treated symptomatically. Also, a treatment of the underlying condition is typically undertaken. Treating the underlying condition may help restore the levels of LGLs in blood, in many cases
• Since, the condition is only short-term; the prognosis of Transient Large Granular Lymphocytosis is normally good with adequate treatment. However, the overall prognosis also depends on the type and severity of the underlying condition and the patient’s response to treatment

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