Progressive Multifocal Leukoencephalitis

Brain & Nerve

Diseases & Conditions

Contributed byKrish Tangella MD, MBAOct 19, 2020

The topic Progressive Multifocal Leukoencephalitis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Progressive Multifocal Leukoencephalopathy.

Quick Summary:

Progressive Multifocal Leukoencephalopathy (PML) is a rare, but fatal brain disease caused by reactivation of the polyomavirus JC in the central nervous system (CNS) of immunocompromised individuals. The disease damages the myelin, material that covers and protects the nerves in the brain
The polyomavirus is a generally harmless virus, except in those with weak immune systems. In such individuals, PML causes clumsiness with progressive weakness, speech and vision defects, difficulties with memory, and personality changes
A diagnosis of PML would include imaging studies of the brain (CT and MRI scan) and examination of cerebrospinal fluid for the presence of the JC virus
There is no specific treatment for Progressive Multifocal Leukoencephalopathy, which leads to acute brain and neurological dysfunction. The prognosis of the condition is very poor, with death typically occurring within 1 to 3 months of disease onset

Please find comprehensive information on Progressive Multifocal Leukoencephalopathy regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

On the Article

Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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