Prion Disease (Kuru)

Prion Disease (Kuru)

Article
Brain & Nerve
Diseases & Conditions
Contributed byMaulik P. Purohit MD MPHNov 20, 2018

The topic Prion Disease (Kuru) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Kuru.

Quick Summary:

  • Kuru is a fatal, irreversible, and degenerative neurological disorder that is caused by an abnormal protein called prions, which is found in the human brain
  • Kuru was commonly found among the people of an island called Papua New Guinea who practiced cannibalism, a practice where the brain of dead people were eaten by their relatives and family members as part of certain funeral ritual
  • The abnormal prion proteins alter the internal structures of the brain cells, causing abnormal functioning of the brain and nervous system
  • The common signs and symptoms associated with Kuru include coordination problems with difficulty in walking, tremors, emotional liability, headache, muscle jerks,  difficulty in speech and swallowing, and many other features
  • A definitive diagnosis of Kuru can only be made either through a brain biopsy or post-mortem exam of brain
  • Kuru is incurable and presently, there is no known treatment for the condition. The prognosis is poor and death usually occurs within a year of onset of the first symptoms 

Please find comprehensive information on Kuru regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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