Primary Cardiac Rhabdomyosarcoma

Primary Cardiac Rhabdomyosarcoma

Article
Heart & Vascular Health
Diseases & Conditions
+2
Contributed byKrish Tangella MD, MBADec 07, 2021

The topic Primary Cardiac Rhabdomyosarcoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Cardiac Rhabdomyosarcoma.

Quick Summary:

  • Cardiac Rhabdomyosarcoma is a very uncommon, high-grade malignant tumor of the heart. The rhabdomyosarcoma (RMS) is an infrequent, but malignant ‘skeletal muscle’ tumor of the soft tissues. The RMS tumors are poorly-defined, fleshy, expanding masses that form deep within the body tissues, or below the skin surface
  • There are 3 types of rhabdomyosarcomas including the embryonal, alveolar, and pleomorphic subtypes. The most common type that is almost always present in the heart is embryonal rhabdomyosarcoma (ERMS). It is a primary tumor that originates within the heart
  • Currently, there are no specific risk factors identified, but ERMS may be associated with certain genetic disorders including Beckwith-Wiedemann syndrome, Costello syndrome, and neurofibromatosis type 1, among others
  • The cause of formation of Cardiac Rhabdomyosarcoma is not well-established. However, it is believed to occur due to certain genetic mutations. These heart tumors are mostly observed in children and young adults and may be found anywhere in the heart (atrium or ventricle)
  • Large-sized tumors may cause chest pain, blood in cough, breathing difficulties, and dizziness. The complications of Rhabdomyosarcoma of Heart include metastasis to various regions/organs of the body and recurrence following surgery to remove them
  • The treatment of Cardiac Rhabdomyosarcoma is undertaken through surgery. However, since it is difficult to remove the entire tumor, chemotherapy and/or radiation therapy may be proposed. The prognosis of Cardiac Rhabdomyosarcoma is generally poor due to local invasion and metastasis of the malignancy to various body sites

Please find comprehensive information on Cardiac Rhabdomyosarcoma regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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