Pancreatic Vasoactive Intestinal Peptide Secreting Tumor

Pancreatic Vasoactive Intestinal Peptide Secreting Tumor

Article
Digestive Health
Cancer & Benign Tumors
+1
Contributed byKrish Tangella MD, MBAApr 04, 2018

The topic Pancreatic Vasoactive Intestinal Peptide Secreting Tumor you are seeking is a synonym, or alternative name, or is closely related to the medical condition VIPoma of Pancreas.

Quick Summary:

  • VIPoma of Pancreas is an extremely rare endocrine tumor of pancreas that secretes vasoactive intestinal peptide (VIP, a hormone). Normally, VIP is secreted by nerves of the central nervous system and nerves in the GI tract, respiratory tract, and urogenital tract
  • 90% of VIPomas arise in the pancreas, while the remaining 10% occur in the gastrointestinal (GI) tract. In the GI tract, the colon is the frequent site of this malignant tumor. In some very rare cases, the tumor is present in the adrenal gland or liver (there is a 1-2% chance of the tumor arising from these locations)
  • VIPoma of Pancreas generally occurs in middle-aged and slightly older individuals, though it may affect children too. These tumors may be small and during the early stages may not cause any significant signs and symptoms
  • VIPoma of Pancreas can cause severe watery diarrhea that is longstanding, severe loss of body fluids, and increased blood calcium and glucose levels. Most tumors may have metastasized during diagnosis to the liver or lungs
  • In majority of cases, a complete surgical excision is the preferred mode of treating this malignant tumor. In cases of metastasis (which takes place frequently), a combination of chemotherapy, radiation therapy, and surgical procedures may be used
  • The prognosis of Pancreatic VIPoma depends upon many factors including the stage of the tumor, the age and overall health of the individual; however, the prognosis is unpredictable

The pancreas is an important organ of the digestive system.

  • Based on function of the pancreas, it can be functionally divided into 2 parts, namely:
    • Exocrine pancreas, which produces digestive enzymes, and
    • Endocrine pancreas that produces hormones such as insulin, glucagon, and somatostatin. Insulin and glucagon helps with controlling sugar levels in blood
  • 95% of the pancreas is exocrine portion and 5% is endocrine portion. Pancreatic tumors (both benign and malignant) can arise from both the exocrine and the endocrine part
  • Based upon anatomy of the pancreas, it can be divided into 3 main parts, namely the:
    • Head,
    • Body, and
    • Tail
  • Pancreatic tumors can affect the head, body, and tail region of the pancreas. Some tumors can affect one area of the pancreas more than the other areas.

Hence, localizing the tumor site can guide the healthcare provider to arrive at a probable diagnosis.

Please find comprehensive information on VIPoma of Pancreas regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

Was this article helpful

On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

0 Comments

Please log in to post a comment.

Related Articles

Test Your Knowledge

Asked by users

Related Centers

Loading

Related Specialties

Loading card

Related Physicians

Related Procedures

Related Resources

Join DoveHubs

and connect with fellow professionals

Related Directories

Who we are

At DoveMed, our utmost priority is your well-being. We are an online medical resource dedicated to providing you with accurate and up-to-date information on a wide range of medical topics. But we're more than just an information hub - we genuinely care about your health journey. That's why we offer a variety of products tailored for both healthcare consumers and professionals, because we believe in empowering everyone involved in the care process.
Our mission is to create a user-friendly healthcare technology portal that helps you make better decisions about your overall health and well-being. We understand that navigating the complexities of healthcare can be overwhelming, so we strive to be a reliable and compassionate companion on your path to wellness.
As an impartial and trusted online resource, we connect healthcare seekers, physicians, and hospitals in a marketplace that promotes a higher quality, easy-to-use healthcare experience. You can trust that our content is unbiased and impartial, as it is trusted by physicians, researchers, and university professors around the globe. Importantly, we are not influenced or owned by any pharmaceutical, medical, or media companies. At DoveMed, we are a group of passionate individuals who deeply care about improving health and wellness for people everywhere. Your well-being is at the heart of everything we do.

© 2023 DoveMed. All rights reserved. It is not the intention of DoveMed to provide specific medical advice. DoveMed urges its users to consult a qualified healthcare professional for diagnosis and answers to their personal medical questions. Always call 911 (or your local emergency number) if you have a medical emergency!