Pancreatic Signet Ring Cell Carcinoma

Pancreatic Signet Ring Cell Carcinoma

Article
Digestive Health
Diseases & Conditions
+2
Contributed byKrish Tangella MD, MBANov 05, 2020

The topic Pancreatic Signet Ring Cell Carcinoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Signet Ring Carcinoma of Pancreas.

Quick Summary:

  • Signet Ring Carcinoma of Pancreas is a very rare, aggressive type of pancreatic cancer. The tumor is called signet ring carcinoma, because the tumor cells have a signet ring pattern, when examined under a microscope by a pathologist. It generally affects elderly men and women
  • Small tumors and those in the early stages may not cause any signs and symptoms. As they grow larger, there may be jaundice, diabetes, loss of appetite, and weight loss, due to this pancreatic tumor
  • Signet Ring Carcinoma of Pancreas can cause complications, such as metastasis to liver and lymph nodes, jaundice, diabetes (if sufficient numbers of islet cells of pancreas are destroyed), and compression of adjoining organs affecting their function
  • In majority of cases, a complete surgical excision is the preferred mode of treating this malignant tumor. In cases of metastasis, a combination of chemotherapy, radiation therapy, and surgical procedures may be used
  • The prognosis of Signet Ring Carcinoma of Pancreas depends upon many factors including the stage of the tumor and overall health of the individual; but, the prognosis is poor

The pancreas is an important organ of the digestive system.

  • Based on function of the pancreas, it can be functionally divided into 2 parts, namely:
    • Exocrine pancreas, which produces digestive enzymes, and
    • Endocrine pancreas that produces hormones such as insulin, glucagon, and somatostatin. Insulin and glucagon helps with controlling sugar levels in blood
  • 95% of the pancreas is exocrine portion and 5% is endocrine portion. Pancreatic tumors (both benign and malignant) can arise from both the exocrine and the endocrine part
  • Based upon anatomy of the pancreas, it can be divided into 3 main parts, namely the:
    • Head,
    • Body, and
    • Tail
  • Pancreatic tumors can affect the head, body, and tail region of the pancreas. Some tumors can affect one area of the pancreas more than the other areas.

Hence, localizing the tumor site can guide the healthcare provider to arrive at a probable diagnosis.

Please find comprehensive information on Signet Ring Carcinoma of Pancreas regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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