Pancreatic Acinar Cell Carcinoma

Pancreatic Acinar Cell Carcinoma

Article
Digestive Health
Cancer & Benign Tumors
+1
Contributed byKrish Tangella MD, MBAMar 12, 2018

The topic Pancreatic Acinar Cell Carcinoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Acinar Cell Carcinoma of Pancreas.

Quick Summary:

  • Acinar Cell Carcinoma of Pancreas is a rare, malignant cancer of the acinar cells of the pancreas. It typically occurs in elderly men
  • It may not cause any signs and symptoms initially. However, over the course of time, it may cause abdominal pain, nausea and vomiting, and lead to weight loss
  • Acinar Cell Carcinoma of Pancreas can cause complications, such as metastasis to liver and lymph nodes and diabetes (if sufficient numbers of islet cells of pancreas are destroyed). Metastasis to the liver can lead to increased lipase secretion from the tumor cells, causing a variety of signs and symptoms
  • In majority of cases, a complete surgical excision is the preferred mode of treating this malignant tumor. In cases of metastasis, a combination of chemotherapy, radiation therapy, and surgical procedures may be used
  • The prognosis of Acinar Cell Carcinoma of Pancreas depends upon many factors including the stage of the tumor and overall health of the individual. The survival rate of individuals with Pancreatic Cancer, Acinar Type is typically poor

The pancreas is an important organ of the digestive system.

  • Based on function of the pancreas, it can be functionally divided into 2 parts, namely:
    • Exocrine pancreas, which produces digestive enzymes, and
    • Endocrine pancreas that produces hormones such as insulin, glucagon, and somatostatin. Insulin and glucagon helps with controlling sugar levels in blood
  • 95% of the pancreas is exocrine portion and 5% is endocrine portion. Pancreatic tumors (both benign and malignant) can arise from both the exocrine and the endocrine part
  • Based upon anatomy of the pancreas, it can be divided into 3 main parts, namely the:
    • Head,
    • Body, and
    • Tail
  • Pancreatic tumors can affect the head, body, and tail region of the pancreas. Some tumors can affect one area of the pancreas more than the other areas.

Hence, localizing the tumor site can guide the healthcare provider to arrive at a probable diagnosis.

Please find comprehensive information on Acinar Cell Carcinoma of Pancreas regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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