Ocular Lymphoma

Ocular Lymphoma

Article
Eye & Vision
Diseases & Conditions
+1
Contributed byMaulik P. Purohit MD MPHMar 29, 2018

The topic Ocular Lymphoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Lymphoma of Eye.

Quick Summary:

  • Lymphoma of Eye is an uncommon lymphoma, which is generally observed in elderly adults. It is also known as Ocular Lymphoma. The condition may affect the conjunctiva, inside structure of eye, eyeball, or tissues around the eye orbit
  • The condition may be primary or secondary:
    • Primary Lymphoma of Eye (also known as Primary Intraocular Lymphoma or PIOL): This type of lymphoma first involves the eye and later can involve other parts of the body including the lymph nodes and bone marrow
    • Secondary Lymphoma of Eye: This type of lymphoma involves other parts of the body first, such as peripheral blood, lymph nodes, bone marrow, and other organs; eye involvement occurs later
  • Lymphoma of Eye can either be a B-cell lymphoma or a T-cell lymphoma. B-cell lymphomas are far more common than T-cell lymphomas
  • There are various (histological) subtypes of Ocular Lymphomas and some of these include:
    • Diffuse large B-cell lymphoma of eye or ocular adnexal DLBCL
    • MALT lymphoma of eye or ocular MALT lymphoma
  • Lymphoma of Eye may be associated with autoimmune disorders. The cause of the condition is generally unknown. It is generally noted to be present with lymphoma affecting the central nervous system
  • It can cause blurred vision, redness of the eyes, burning sensation, and other general signs and symptoms, such as fever, weight loss, and appetite loss. In case of severe complications, it may result in vision loss
  • Chemotherapy, surgery, radiation therapy, and other treatment measures may be used for treating Lymphoma of Eye based on the assessment of the physician. Additionally, treatment for any underlying condition will also be considered by the healthcare provider
  • The prognosis depends on many factors including the subtype and stage of lymphoma, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis of Lymphoma of Eye is guarded

General information on lymphoma and lymphocytes:

  • Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
    • Hodgkin lymphoma
    • Non-Hodgkin lymphoma
  • Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
  • Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Gastrointestinal Follicular Lymphoma arises from cancerous B-cells
  • Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
  • There are 3 different kinds of lymphocytes:
    • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
    • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
    • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

Please find comprehensive information on Lymphoma of Eye regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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