The topic Non-Alcoholic Steatohepatitis in Children you are seeking is a synonym, or alternative name, or is closely related to the medical condition Pediatric Non-Alcoholic Steatohepatitis.

Quick Summary:

• Pediatric Non-Alcoholic Steatohepatitis (Pediatric NASH) is a form of non-alcoholic steatohepatitis (NASH) that affects children and adolescents (more common in prepubertal males). NASH is also seen in adults
• NASH is a condition on the spectrum of non-alcoholic fatty liver diseases (NAFLD). The spectrum includes:
  • Steatosis (fatty liver)
  • NASH (fatty liver with accompanying inflammation)
  • Cirrhosis (irreversible liver scarring)
  • And eventually, hepatocellular carcinoma (liver cancer)           
• NASH is characterized by fat accumulation (steatosis) followed by inflammation (hepatitis) due to unknown reasons, other than alcohol, drugs, and medications. This inflammation can derange liver function and damage the liver structure
• Pediatric NASH is divided into two types:
  • Type 1 Pediatric NASH: Type 1 Pediatric NASH shows liver biopsies that resemble adult NASH
  • Type 2 Pediatric NASH: Type 2 Pediatric NASH shows liver biopsies that are unique in appearance        
• Obesity, diabetes mellitus, insulin resistance, hypertriglyceridemia, and being a male, all increase one’s risk of developing the condition. However, the cause of Pediatric Non-Alcoholic Steatohepatitis is unknown
• Typically, individuals with Pediatric NASH do not have any symptoms, which make it difficult to diagnose the condition. NASH in Children is usually identified during routine checkups and confirmed by blood tests, imaging tools, or liver biopsies
• Pediatric NASH may be treated through a combination of weight loss programs, medications to treat diabetes mellitus, vitamin E, and using other medications. Most children with the condition have a good prognosis, when lifestyle changes are made to control weight. Untreated or severe progressive conditions may lead to liver cirrhosis and liver failure

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