Multiple System Atrophy - Cerebellar Predominance

Multiple System Atrophy - Cerebellar Predominance

Article
Brain & Nerve
Diseases & Conditions
+2
Contributed byKrish Tangella MD, MBAAug 29, 2023

The topic Multiple System Atrophy - Cerebellar Predominance you are seeking is a synonym, or alternative name, or is closely related to the medical condition Hereditary Olivopontocerebellar Atrophy.

Quick Summary:

  • Olivopontocerebellar Atrophy (OPCA) is a group of neurodegenerative disorders that causes the cerebellum, pons, inferior olivae, and other parts of the brain to deteriorate
    • The cerebellum is responsible for maintaining balance and coordinating voluntary movement
    • The pons is responsible for coordinating nerve signals between structures of the brain
    • The inferior olivae is involved with balance, coordination, and motor activity
  • As these structures begin to deteriorate, signs and symptoms, such as ataxia (loss of control of bodily movement), balance issues, and neuropathy (nerve damage) occur. OPCA is a progressive disorder and the signs and symptoms get worse over time
  • Hereditary Olivopontocerebellar Atrophy can be caused by the inheritance of autosomal dominant, autosomal recessive, or X linked recessive genes. Since it is a genetic condition, a family history of Hereditary OPCA increases the risk for an individual to be affected
  • Generally, men are more likely to be affected by Hereditary Olivopontocerebellar Atrophy than women; the disorder usually begins to present itself in the late 20s
  • A healthcare provider can diagnose the condition through a physical exam, along with an analysis of previous medical history. Upon diagnosis, the treatment options are symptomatic, as there is no cure for Hereditary Olivopontocerebellar Atrophy
  • Additionally, treatment is used to help prevent complications, such as choking, infection of the lungs from inhaling food, and physical injuries. Treatment can include medications for specific symptoms, therapy to help with speech and balance, and use of walking aids
  • The prognosis for Hereditary Olivopontocerebellar Atrophy is generally poor as the central nervous system deterioration leads to severe disability; the condition is often fatal

Please find comprehensive information on Hereditary Olivopontocerebellar Atrophy regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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