MiT Family Translocation Kidney Cancer in Adults

MiT Family Translocation Kidney Cancer in Adults

Article
Kidney & Bladder Health
Diseases & Conditions
+2
Contributed byKrish Tangella MD, MBAJan 24, 2020

The topic MiT Family Translocation Kidney Cancer in Adults you are seeking is a synonym, or alternative name, or is closely related to the medical condition MiT Family Translocation Renal Cell Carcinoma in Adults.

Quick Summary:

  • MiT Family Translocation Renal Cell Carcinoma in Adults (or MFTRCC in Adults) is a rare and aggressive type of renal cell carcinoma (kidney cancer) that develops from the renal cortex. It is a malignant tumor that develops due to an abnormality within the tissue lining in the tubules of the kidney
  • By definition, MiT Family Translocation Renal Cell Carcinoma in Adults has mutations involving the TFE 3 gene, TFE B gene, TFC gene, and MiTF gene. The tumor specimens can have different microscopic features when examined under a microscope
  • The cause of development of MiT Family Translocation Renal Cell Carcinoma in Adults is reportedly due to genetic mutations. Genetic testing may be required to establish a diagnosis of the condition. MFTRCC in Adults affects both male and female adults and they constitute about 3% of all adult renal cell carcinomas
  • The risk factors for the development of MiT Family Translocation Renal Cell Carcinoma in Adults are not well-established. However, some of the general risk factors for kidney tumors include a family history of the condition (that may result in hereditary Adult MFTRCC), smoking, exposure to toxins due to cytotoxic chemotherapy, high blood pressure, and even obesity
  • The typical signs and symptoms of MiT Family Translocation Renal Cell Carcinoma in Adults include blood in urine, a lump on the side (abdomen), unexplained fever, flank pain, and inexplicable weight loss. MFTRCC in Adults may give rise to complications, such as cancer spread to other parts of the body
  • The treatment options for the condition may include surgery, radiation therapy, chemotherapy, and targeted drug therapy. The prognosis of MiT Family Translocation Renal Cell Carcinoma in Adults depends on a variety of factors including the type and size of tumor, whether it is localized to the kidneys or has metastasized to other body regions (if the condition is in its early stage or advanced stage, at the time of diagnosis)
  • Although MiT Family Translocation Renal Cell Carcinoma in Adults might not be preventable, being aware of one’s family history and having regular check-ups might help in an early diagnosis. Moreover, leading a healthy lifestyle, managing an ideal body weight, controlling blood pressure, avoiding unnecessary medication, smoking cessation, and other such measures can help one reduce the risk for cancer formation

Please find comprehensive information on MiT Family Translocation Renal Cell Carcinoma in Adults regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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