The topic Mendes da Costa Syndrome you are seeking is a synonym, or alternative name, or is closely related to the medical condition Erythrokeratoderma Variabilis.

Quick Summary:

• Erythrokeratoderma is a benign skin condition, wherein as the name suggests, the skin is red (erythematous) and thickened with the presence of scaling (or hyperkeratosis). The skin condition is considered to be a pattern of skin findings and not a disease/condition in itself
• Erythrokeratoderma Variabilis (EKV) may be described as the most common variant (or major subtype) of erythrokeratoderma. It is caused by inherited or sporadic genetic mutations
• The signs and symptoms may be present at birth or within the first 12 months of birth. It is a slowly-progressing condition, and hence, it is also known as Erythrokeratodermia Variabilis Et Progressiva (EKVP)
• The skin redness and thickening can be focal (localized) or widespread (diffused) and the manifestation is in the form of red flaky plaques or patches. Any part of the body skin may be affected
• A diagnosis of Erythrokeratoderma Variabilis can be made by clinical exam, skin exam, and various other diagnostic tools including dermoscopy and wood’s lamp examination. Genetic testing to identify the genes associated with the disorder may be undertaken
• Erythrokeratoderma Variabilis is an incurable condition. However, following puberty, the signs and symptoms are known to remain stable and they do not get worse. The skin condition may be treated using moisturizers, topical creams, and keratolytics
• The prognosis of Erythrokeratoderma Variabilis Et Progressiva depends upon the severity of the symptoms. However, with adequate treatment, the prognosis is generally good

Please find comprehensive information on Erythrokeratoderma Variabilis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.