The topic Medication-Induced Thrombocytopenia you are seeking is a synonym, or alternative name, or is closely related to the medical condition Drug-Induced Thrombocytopenia.

Quick Summary:

• Drug-Induced Thrombocytopenia (DIT) is a condition in which a drug or medication causes a decrease in the number of platelets in blood. This may result in a bleeding disorder. Platelets are blood cells that are responsible for the clotting process in the body
• Individuals, who use certain antibiotics (such as penicillin), painkillers (anti-inflammatory drugs), non-steroidal drugs, medicines for ulcers (ranitidine) and synthetic drugs, such as sulfonamides, are more susceptible to DIT
• Drug-Induced Thrombocytopenia can be caused by drugs, which can either interfere with the generation of platelets, or destroy the existing platelets. The drugs may damage platelets by two mechanisms
  • In the first type, antibodies to platelets are produced by the immune system. This drug-induced anti-platelet antibodies cause immune-mediated thrombocytopenia (IMT)
  • In the second type, the drugs destroy platelets in a non-immune mediated mechanism
• Spontaneous, abnormal and continuous bleeding, excessive bleeding from minor injuries, purple spots on the skin, and susceptibility to easy bruising are some symptoms of Drug-Induced Thrombocytopenia. The potential complications from DIT include bleeding in the brain or gastrointestinal tract, which can be serious
• In order to diagnose the condition, a healthcare professional may perform a thorough physical exam with complete clinical history (including evaluation of medications being taken), request blood tests, and undertake blood clotting studies. If necessary, a biopsy of the bone marrow may be ordered
• Since DIT is caused by drugs, discontinuation of the causative drug may be recommended. Additionally, treatment measures including platelet transfusion, plasmapheresis, and corticosteroid medication may be required, in some cases of severe hemorrhage, to bring platelet count to normal range and prevent further bleeding episodes
• The prognosis of Drug-Induced Thrombocytopenia is usually excellent, if the drug that caused the condition is identified early and subsequently avoided. The healthcare provider may recommend alternate medication to replace the causative drug

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