The topic Lymphoma of Small Bowel you are seeking is a synonym, or alternative name, or is closely related to the medical condition Lymphoma of Small Intestine.

Quick Summary:

• Lymphoma of Small Intestine is an uncommon lymphoma, which is generally observed in elderly men and women. It is also known as Small Bowel Lymphoma and is the most common malignancy of the small bowel
• The condition may be primary (less common) or secondary (more common):
  • Primary Lymphoma of Small Intestine: This type of lymphoma first involves the small intestine and later can involve other parts of the body including the lymph nodes and bone marrow
  • Secondary Lymphoma of Small Intestine: This type of lymphoma involves other parts of the body first, such as peripheral blood, lymph nodes, bone marrow, and other organs; small intestinal involvement occurs later
• Lymphoma of Small Intestine can either be a B-cell lymphoma or a T-cell lymphoma. B-cell lymphomas are far more common than T-cell lymphomas
• There are various (histological) subtypes of Small Intestinal Lymphomas and some of these include:
  • MALT lymphoma of small intestine, which is the most common subtype
  • Diffuse large B-cell lymphoma of small intestine
  • Follicular lymphoma of small intestine
  • Burkitt lymphoma of small intestine
  • Mantle cell lymphoma of small intestine
• Lymphoma of Small Intestine may be associated with various conditions such as inflammatory bowel diseases, Helicobacter or EBV infections, and autoimmune disorders. Some lymphomas are also known to be associated with celiac sprue and HIV infection (immunodeficiency disease)
• It can cause abdominal pain, diarrhea, gastrointestinal tract bleeding, and other general signs and symptoms, such as fever, weight loss, and appetite loss. Severe cases may result in rupture and perforation of the small intestine
• Chemotherapy, surgery, radiation therapy, and other treatment measures may be used for treating Lymphoma of Small Intestine based on the assessment of the physician. If the condition is associated with any underlying condition (such as viral or bacterial infections, autoimmune disorders, etc.), then suitable treatment for the condition will also be administered
• The prognosis depends on many factors including the subtype and stage of lymphoma, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis of Lymphoma of Small Intestine is guarded

General information on lymphoma and lymphocytes:

• Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
• Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
• Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Gastrointestinal Follicular Lymphoma arises from cancerous B-cells
• Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
• There are 3 different kinds of lymphocytes:
  • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
  • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
  • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

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