Large Cell Neuroendocrine Carcinoma of Uterine Corpus

Large Cell Neuroendocrine Carcinoma of Uterine Corpus

Article
Women's Health
Diseases & Conditions
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Contributed byMaulik P. Purohit MD MPHJun 09, 2020

The topic Large Cell Neuroendocrine Carcinoma of Uterine Corpus you are seeking is a synonym, or alternative name, or is closely related to the medical condition Large Cell Neuroendocrine Carcinoma of Uterus.

Quick Summary:

  • Large Cell Neuroendocrine Carcinoma of Uterus (LCNEC of Uterus) is a rare subtype of neuroendocrine endometrial cancer. They are usually high-grade tumors that arise from the body of the uterus. When examined by a pathologist under the microscope, the tumor consists of large neuroendocrine cells
  • Even though there are no specific risk factors for the development of Large Cell Neuroendocrine Carcinoma of Uterus, there are generally established risk factors for endometrial cancers including obesity, poorly-controlled diabetes, positive family history of endometrial cancer, and polycystic ovarian syndrome. The exact cause of the cancer is unknown, but it may be due to certain genetic abnormalities
  • Most these tumors are detected and diagnosed in women aged 50 years and older (postmenopausal women). The majority of Large Cell Neuroendocrine Carcinoma of Uterus cases are detected and diagnosed at an early stage due to frequent abnormal vaginal bleeding, which is a major indicative sign. Additional signs and symptoms may include pelvic pain, pain during sex, and urination difficulties
  • If Large Cell Neuroendocrine Carcinoma of Uterus is diagnosed early, then a surgical removal of the uterus usually eliminates the cancer. The earlier the stage of cancer at detection and the lower the grade of the cancer, the better is the prognosis. In general, Uterine Large Cell Neuroendocrine Carcinoma has a poorer prognosis compared to other subtypes of endometrial cancers

Please find comprehensive information on Large Cell Neuroendocrine Carcinoma of Uterus regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH picture
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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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