The topic Large Cell Anaplastic Carcinoma of Lung you are seeking is a synonym, or alternative name, or is closely related to the medical condition Large Cell Carcinoma of Lung.

Quick Summary:

• Lung cancer is a high mortality cancer that affects the lungs. Any individual can develop lung cancer, although individuals who smoke cigarettes remain at the highest risk for the condition. It is the most common cause of cancer-related death in the world
• Large Cell Carcinoma of Lung is a type of lung cancer described as an undifferentiated non-small cell carcinoma (NSCC) without having the histological features of any of the following types:
  • Adenocarcinoma
  • Small cell carcinoma
  • Squamous cell carcinoma
• The diagnosis of Large Cell Carcinoma of Lung is often a diagnosis of exclusion. According to the WHO, a definitive diagnosis of this carcinoma can only be made on a surgically-biopsied (thoroughly-sampled) tumor specimen, which is then examined under a microscope by a pathologist
• Many lung tumors previously regarded as subtypes of large cell carcinoma have been regrouped appropriately based on newer research findings. These include the following types:
  • Basaloid carcinoma
  • Large cell neuroendocrine carcinoma
  • Lymphoepithelioma-like tumor
  • Clear cell and rhabdoid tumors
• The cause of Large Cell Carcinoma of Lung is generally unknown, but it is influenced by smoking. The carcinoma can cause chest pain, breathing difficulties, fatigue, and other general signs and symptoms, such as fever, weight loss, and appetite loss
• Chemotherapy, surgery, radiation therapy, and other treatment measures may be used for treating Large Cell Carcinoma of Lung based on the assessment of the physician
• The prognosis depends on many factors including the subtype, grade and stage of the tumor, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis of Large Cell Carcinoma of Lung is guarded

There are 3 histological subtypes of Large Cell Carcinoma of Lung (based on immunohistochemical profile) and these include the following:

• Large Cell Carcinoma of Lung with null immunohistochemical features
• Large Cell Carcinoma of Lung with unclear immunohistochemical features
• Large Cell Carcinoma of Lung with no additional stains

These subtypes dictate the type of therapy that may be used in treating the cancer and can influence the tumor outcomes.

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