The topic IDH-Mutant Diffuse Astrocytoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Diffuse Astrocytoma, IDH Mutant type.

Quick Summary:

• A diffuse astrocytoma (DA) is a form of brain tumor. A brain tumor may be described as a mass of abnormally growing cells arising from the brain tissue (brain parenchyma and meninges) or the spinal cord (central spine). The brain along-with the spinal cord constitute the central nervous system (CNS) of the body
• Broadly, brain tumors are classified as benign (non-cancerous) and malignant. Malignant tumors are cancerous and can spread or metastasize to other regions of the body. They generally exhibit rapid growth and, in some cases, may present symptoms during the early stages of development
• The World Health Organization (WHO) classifies central nervous system tumors according to their grade and histological subtypes. The diagnosis of a tumor subtype is made by the pathologist after examining a tissue biopsy of the tumor under a microscope. This WHO classification system is used by healthcare professionals all over the world in diagnosing and treating these tumors
• Diffuse Astrocytoma, IDH-Mutant type is a slow-growing brain tumor that arises from the glial cells (a type of brain cells). The tumor is characterized by mutations on IDH1 or IDH2 genes without 1p/19q chromosome codeletions. It is commonly observed in young adults, arising from the cerebral hemispheres of the brain. Per WHO classification, the tumor forms a part of “diffuse astrocytic and oligodendroglial tumors”
• Diffuse Astrocytomas, IDH-Mutant types are WHO grade II brain tumors, meaning they are low-grade tumors. The grade II tumors grow faster than grade I tumors; grade I tumors are considered to be the most benign of the brain tumors. Grade II tumors tend to be minimally infiltrative into the surrounding brain tissue but have the possibility to recur as a higher grade tumor following treatment. It is less likely to grow and spread than malignant tumors
• The cause of formation of IDH-Mutant Diffuse Astrocytoma is not well-established. It is reported that a combination of several factors may play a role in their formation, including genetic, environmental, and lifestyle-related. The risk factors may include the presence of certain genetic disorders, exposure to ionized radiation, viral infections, and even head trauma
• There is a gradual onset of signs and symptoms observed in many cases of Diffuse Astrocytoma, IDH-Mutant type. This may also depend on the location of the tumor. Individuals may experience headaches, weakness in different parts of the body, convulsions, vision and speech disturbances. Large-sized tumors may compress adjacent brain tissue resulting in complications
• The treatment modalities for Diffuse Astrocytoma, IDH-Mutant type may include surgery, radiation therapy, and the administration of certain drugs to slow progression of the tumor. The prognosis is determined by a wide variety of factors; children and young adults are known to have an overall better prognosis than older adults

Please find comprehensive information on Diffuse Astrocytoma, IDH Mutant type regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.