The topic Hypoprothrombinemia you are seeking is a synonym, or alternative name, or is closely related to the medical condition Factor II Deficiency.

Quick Summary:

In normal cases, when an individual bleeds, there are mechanisms in place to stop bleeding. The blood clotting process is summarized below:

• One of the blood cells is platelets. The platelets gather together (aggregate) and get attached to the blood vessels that are bleeding, to form a plug (hemostatic plug)
• Following this, certain proteins present in the liquid portion of the blood (called coagulation factors), assemble on top of the plug and reinforce the plug by a “mesh-like” formation, which then stops the bleeding
• Factor II (F II or prothrombin) is one of the 13 major coagulation factors (numbered from I to XIII). These coagulation factors have to be activated in a complex sequence (coagulation cascade) to form the clot ultimately. A deficiency or non-functioning of any of the clotting factors can cause abnormal bleeding

Factor II (Prothrombin) Deficiency is a very rare bleeding disorder, which is usually inherited from parents or acquired (non-inherited). A congenital deficiency of Factor II or a decreased production in the body of Factor II, due to a variety of reasons, can lead to Factor II Deficiency disorder

• Signs and symptoms of this condition include bleeding at birth from the umbilical cord, excess bleeding after delivery of child, heavy or excess menstrual bleeding, bleeding after a surgery, spontaneous bruising, bleeding in the nose, etc.
• Uncommon sites of bleeding include muscle, brain, joints, abdomen or other sites, and the condition may present with signs and symptoms specific to that site
• The treatment of the condition may include education and awareness. Also, fresh frozen plasma or prothrombin concentrates may be given to control active bleeding. Vitamin K supplement may be helpful in acquired F II Deficiency
• The prognosis of F II Deficiency (both inherited and non-inherited) is generally good with appropriate treatment

Please find comprehensive information on Factor II Deficiency regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.